Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50002615
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50023323(2,3-Dimethyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8...)
Affinity DataIC50: 100nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50021516(CHEMBL291332 | 2,5-Bis-(3,4,5-trimethoxy-phenyl)-t...)
Affinity DataIC50: 180nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50023325(2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...)
Affinity DataIC50: 200nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019687(CHEMBL1202755 | CHEMBL57825)
Affinity DataIC50: 250nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019665(CHEMBL1204215 | CHEMBL56588 | 2,3-Dimethyl-11-oxo-...)
Affinity DataIC50: 250nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019669(CHEMBL57736 | 2-Isopropyl-11-oxo-11H-pyrido[2,1-b]...)
Affinity DataIC50: 350nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019678(CHEMBL56418 | 3-Methoxy-11-oxo-11H-pyrido[2,1-b]qu...)
Affinity DataIC50: 370nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50023315(2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...)
Affinity DataIC50: 400nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019684(CHEMBL417781 | CHEMBL1204214 | 2-Isopropyl-11-oxo-...)
Affinity DataIC50: 400nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019686(CHEMBL294706 | 2-Isopropyl-11-oxo-11H-pyrido[2,1-b...)
Affinity DataIC50: 450nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019676(CHEMBL300338 | 2-Methyl-11-oxo-11H-pyrido[2,1-b]qu...)
Affinity DataIC50: 500nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50006048(CV-3988 | 2-methoxy-3-(octadecylcarbamoyloxy)propy...)
Affinity DataIC50: 600nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019671(CHEMBL57716 | 2-Isopropoxy-11-oxo-11H-pyrido[2,1-b...)
Affinity DataIC50: 600nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50023324(2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...)
Affinity DataIC50: 600nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019688(CHEMBL58518 | 2-Bromo-11-oxo-11H-pyrido[2,1-b]quin...)
Affinity DataIC50: 700nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019680(CHEMBL56932 | CHEMBL1204216 | 2-Isopropyl-11-oxo-1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019689(CHEMBL57489 | 3-Chloro-11-oxo-11H-pyrido[2,1-b]qui...)
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50023321(5-{4-[(2,3-Dimethyl-11-oxo-11H-pyrido[2,1-b]quinaz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019673(CHEMBL60930 | 2-Isopropyl-11-oxo-11H-pyrido[2,1-b]...)
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50023322(1-{6-[(2,3-Dimethyl-11-oxo-11H-pyrido[2,1-b]quinaz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50023319(2-Isopropyl-8-(6-pyridin-3-yl-hexyl)-pyrido[2,1-b]...)
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50023320(3-{4-[(2,3-Dimethyl-11-oxo-11H-pyrido[2,1-b]quinaz...)
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50023318(2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50023317(2-Isopropyl-11-oxo-11H-pyrido[2,1-b]quinazoline-8-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50023316(2-Isopropyl-8-[(4-pyridin-3-yl-butylamino)-methyl]...)
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019672(CHEMBL1204213 | CHEMBL60764 | 2-Isopropyl-11-oxo-1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019675(CHEMBL293362 | 2-Methoxy-11-oxo-11H-pyrido[2,1-b]q...)
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019670(CHEMBL57480 | 2-Hydroxy-11-oxo-11H-pyrido[2,1-b]qu...)
Affinity DataIC50: 1.20E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019677(CHEMBL301215 | 2-Isopropyl-11-oxo-11H-pyrido[2,1-b...)
Affinity DataIC50: 1.20E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019668(CHEMBL57072 | CHEMBL1204224 | 2-Isopropyl-11-oxo-1...)
Affinity DataIC50: 1.30E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019683(CHEMBL60625 | 11-Oxo-11H-pyrido[2,1-b]quinazoline-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019690(CHEMBL1204218 | CHEMBL418141 | 2-Isopropyl-11-oxo-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019681(CHEMBL1204223 | CHEMBL56434 | 2-Isopropyl-11-oxo-1...)
Affinity DataIC50: 3.50E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-activating factor receptor(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50019679(CHEMBL56742 | 2-Isopropyl-11-oxo-11H-pyrido[2,1-b]...)
Affinity DataIC50: 5.00E+3nMAssay Description:Ability to inhibit platelet activating factor (PAF) binding to platelets by 50% was determined by using [3H]PAF as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed