Compile Data Set for Download or QSAR
Report error Found 143 Enz. Inhib. hit(s) with all data for entry = 50018503
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608795(CHEMBL5290993)
Affinity DataEC50:  0.180nMAssay Description:Agonist activity at D4R (unknown origin) by camp reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50257034(CHEMBL4096543)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]-spiperone from D4 (unknown origin) receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50401953(CHEMBL2207643)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM85093(NSC_3853 | CHEMBL267014 | CAS_3853 | CHEMBL555670 ...)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in HEK293 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608788(CHEMBL5285358)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50094505(2-(4-Phenyl-piperazin-1-ylmethyl)-1H-indole-5-carb...)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608785(CHEMBL5272162)
Affinity DataKi:  0.660nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608786(CHEMBL5278853)
Affinity DataKi:  0.760nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50094503(2-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-in...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608802(CHEMBL5277789)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to D3R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50004770(CHEMBL2312227)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at D4R (unknown origin) by camp reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608787(CHEMBL5280364)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50150141(2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in HEK293 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50109943(3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-pyraz...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608803(CHEMBL2005767)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in HEK293 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608802(CHEMBL5277789)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at D4R (unknown origin) by camp reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50119970(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-((R)-2-me...)
Affinity DataKi:  2nMAssay Description:Binding affinity to D4R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50147929(4-(4-Bromo-benzyl)-2-(4-chloro-2-methoxy-phenoxyme...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50119934(1-(2-Methyl-2,3-dihydro-indol-1-yl)-2-[1-(4-nitro-...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-nemonapride from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50102712(4-(4-Chloro-phenyl)-1-pyrazolo[1,5-a]pyridin-2-ylm...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50153259(CHEMBL184158 | CHEMBL362542 | 2-[4-(4-[3H]-2-cyano...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50147932(4-(4-Chloro-benzyl)-2-(4-chloro-2-methoxy-phenoxym...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM85067(CAS_170856-41-4 | PNU 96415E | CHEMBL81330 | PNU-9...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-nemonapride from human D4 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608794(UCSF924)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-methylspiperone from D4 (unknown origin) receptor expressed in HEK293T cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50073805(FAUC 113 | 3-[4-(4-Chloro-phenyl)-piperazin-1-ylme...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50069041(CP-293019 | (7R,9aS)-7-(4-Fluoro-phenoxymethyl)-2-...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to human D4R assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50050476(4-[5-(4-Chloro-phenyl)-4-methyl-isoxazol-3-yl]-1-p...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in HEK293 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608792(CHEMBL146246)
Affinity DataKi:  3.60nMAssay Description:Binding affinity to D4R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50401953(CHEMBL2207643)
Affinity DataEC50:  3.70nMAssay Description:Agonist activity at human D4R assessed as [35S] GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50124932(5-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1,2,6,7-tet...)
Affinity DataKi:  4nMAssay Description:Binding affinity to D4R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50092051(3-[4-(4-Chloro-benzyl)-piperazin-1-yl]-1-methyl-3,...)
Affinity DataKi:  4nMAssay Description:Binding affinity to D4R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50153259(CHEMBL184158 | CHEMBL362542 | 2-[4-(4-[3H]-2-cyano...)
Affinity DataKi:  4nMAssay Description:Binding affinity to D34 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608794(UCSF924)
Affinity DataEC50:  4.20nMAssay Description:Agonist activity at D4R (unknown origin) by camp reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608795(CHEMBL5290993)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]-methylspiperone from D4 (unknown origin) receptor expressed in HEK293T cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50083342(7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4H-be...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608789(CHEMBL1616116)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50058225(N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...)
Affinity DataEC50:  6.90nMAssay Description:Agonist activity at human D4R expressed in HEK293 cells by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50145081(2-[4-(2-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...)
Affinity DataEC50:  7.20nMAssay Description:Agonist activity at human D2R expressed in HEK293 cells incubated for 3 mins by FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50153259(CHEMBL184158 | CHEMBL362542 | 2-[4-(4-[3H]-2-cyano...)
Affinity DataEC50:  7.5nMAssay Description:Agonist activity at human D4R expressed in HEK293 cells by calcium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50004770(CHEMBL2312227)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]N-methylspiperone from D4 (unknown origin) receptor expressed in HEK293 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50070517(3-{2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-yl]-ethy...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity to D4R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608798(CHEMBL5272829)
Affinity DataEC50:  10nMAssay Description:Agonist activity at D4R (unknown origin) by camp reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608802(CHEMBL5277789)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]N-methylspiperone from D4 (unknown origin) receptor expressed in HEK293 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50145078(2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human D2R expressed in HEK293 cells incubated for 3 mins by FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50145075(2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benz...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human D2R expressed in HEK293 cells incubated for 3 mins by FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50004770(CHEMBL2312227)
Affinity DataKi:  13nMAssay Description:Binding affinity to D3R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50058225(N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO-K1 cells assessed as inhibition constant measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608797(CHEMBL5267339)
Affinity DataEC50:  17nMAssay Description:Agonist activity at D4R (unknown origin) by camp reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
University of Camerino

Curated by ChEMBL
LigandPNGBDBM50608796(CHEMBL5278957)
Affinity DataEC50:  24nMAssay Description:Agonist activity at D4R (unknown origin) by camp reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
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