Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50018227
Affinity DataIC50: 0.100nMAssay Description:Inhibition of DHCR7 (unknown origin)More data for this Ligand-Target Pair
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Human)
Gitam (Deemed To Be University)
Curated by ChEMBL
Gitam (Deemed To Be University)
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of EBP (unknown origin)More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Gitam (Deemed To Be University)
Curated by ChEMBL
Gitam (Deemed To Be University)
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of human DNA polymerase beta by fluorescence anisotropyMore data for this Ligand-Target Pair
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Human)
Gitam (Deemed To Be University)
Curated by ChEMBL
Gitam (Deemed To Be University)
Curated by ChEMBL
Affinity DataIC50: 9.40nMAssay Description:Inhibition of EBP (unknown origin)More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Gitam (Deemed To Be University)
Curated by ChEMBL
Gitam (Deemed To Be University)
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Gitam (Deemed To Be University)
Curated by ChEMBL
Gitam (Deemed To Be University)
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of DHCR7 (unknown origin)More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Gitam (Deemed To Be University)
Curated by ChEMBL
Gitam (Deemed To Be University)
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Human)
Gitam (Deemed To Be University)
Curated by ChEMBL
Gitam (Deemed To Be University)
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of EBP (unknown origin)More data for this Ligand-Target Pair
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Human)
Gitam (Deemed To Be University)
Curated by ChEMBL
Gitam (Deemed To Be University)
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of EBP (unknown origin)More data for this Ligand-Target Pair
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Human)
Gitam (Deemed To Be University)
Curated by ChEMBL
Gitam (Deemed To Be University)
Curated by ChEMBL
Affinity DataIC50: 188nMAssay Description:Inhibition of EBP (unknown origin)More data for this Ligand-Target Pair
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Human)
Gitam (Deemed To Be University)
Curated by ChEMBL
Gitam (Deemed To Be University)
Curated by ChEMBL
Affinity DataIC50: 303nMAssay Description:Inhibition of EBP (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of APC (303 to 739 residues) (unknown origin) preincubated for 60 mins followed by substrate addition and measured after 60 mins using Ac-...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Gitam (Deemed To Be University)
Curated by ChEMBL
Gitam (Deemed To Be University)
Curated by ChEMBL
Affinity DataIC50: 850nMAssay Description:Inhibition of TNKS2 (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Human)
Gitam (Deemed To Be University)
Curated by ChEMBL
Gitam (Deemed To Be University)
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EBP (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of DHCR7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of APC (303 to 739 residues) (unknown origin) preincubated for 60 mins followed by substrate addition and measured after 60 mins using Ac-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of DHCR7 (unknown origin)More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Gitam (Deemed To Be University)
Curated by ChEMBL
Gitam (Deemed To Be University)
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of TNKS1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of DHCR7 (unknown origin)More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Gitam (Deemed To Be University)
Curated by ChEMBL
Gitam (Deemed To Be University)
Curated by ChEMBL
Affinity DataIC50: 6.58E+3nMAssay Description:Inhibition of recombinant full length wild type human Flag-tagged USP7 expressed in human HEK293 cells using Ub-AMC as substrate by fluorometric assa...More data for this Ligand-Target Pair
Affinity DataIC50: 7.97E+3nMAssay Description:Inhibition of APC (303 to 739 residues) (unknown origin) preincubated for 60 mins followed by substrate addition and measured after 60 mins using Ac-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of APC (303 to 739 residues) (unknown origin) preincubated for 60 mins followed by substrate addition and measured after 60 mins using Ac-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of APC (303 to 739 residues) (unknown origin) preincubated for 60 mins followed by substrate addition and measured after 60 mins using Ac-...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DHCR7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of DHCR7 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human DNA polymerase beta using 32P-labeled 63-mer F-DNA substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human DNA polymerase beta using 32P-labeled 63-mer F-DNA substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human DNA polymerase beta using 32P-labeled 63-mer F-DNA substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human DNA polymerase beta using 32P-labeled 63-mer F-DNA substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of APC (303 to 739 residues) (unknown origin) preincubated for 60 mins followed by substrate addition and measured after 60 mins using Ac-...More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of APC (303 to 739 residues) (unknown origin) assessed as inhibition constant preincubated for 60 mins followed by substrate addition and ...More data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:Inhibition of APC (303 to 739 residues) (unknown origin) assessed as inhibition constant preincubated for 60 mins followed by substrate addition and ...More data for this Ligand-Target Pair
Affinity DataKi: 2.41E+3nMAssay Description:Inhibition of APC (303 to 739 residues) (unknown origin) assessed as inhibition constant preincubated for 60 mins followed by substrate addition and ...More data for this Ligand-Target Pair
Affinity DataKi: 3.12E+3nMAssay Description:Inhibition of APC (303 to 739 residues) (unknown origin) assessed as inhibition constant preincubated for 60 mins followed by substrate addition and ...More data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMAssay Description:Inhibition of APC (303 to 739 residues) (unknown origin) assessed as inhibition constant preincubated for 60 mins followed by substrate addition and ...More data for this Ligand-Target Pair
Affinity DataKi: 4.46E+4nMAssay Description:Inhibition of APC (303 to 739 residues) (unknown origin) assessed as inhibition constant preincubated for 60 mins followed by substrate addition and ...More data for this Ligand-Target Pair
