Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50012495
LigandPNGBDBM50557930(CHEMBL4740028)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human TRKA at active state by kinetic based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557930(CHEMBL4740028)
Affinity DataKi:  1nMAssay Description:Inhibition of human TRKA at inactive state by kinetic based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557930(CHEMBL4740028)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human TRKA kinase domain by HTRF KinEASE biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557930(CHEMBL4740028)
Affinity DataIC50: 21nMAssay Description:Inhibition of human TRKA at inactive state assessed as inhibition of substrate phosphorylation using fluorescently-labelled peptide as substrate by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557927(CHEMBL4788009)
Affinity DataIC50: 39nMAssay Description:Inhibition of human TRKA kinase domain by HTRF KinEASE biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557930(CHEMBL4740028)
Affinity DataIC50: 45nMAssay Description:Inhibition of human TRKA at active state assessed as inhibition of substrate phosphorylation using fluorescently-labelled peptide as substrate by cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557928(CHEMBL4800240)
Affinity DataIC50: 47nMAssay Description:Inhibition of human TRKA kinase domain by HTRF KinEASE biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557927(CHEMBL4788009)
Affinity DataKi:  66nMAssay Description:Inhibition of human TRKA at inactive state by kinetic based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557932(CHEMBL4793897)
Affinity DataIC50: 76nMAssay Description:Inhibition of human TRKA at active state assessed as inhibition of substrate phosphorylation using fluorescently-labelled peptide as substrate by cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50557932(CHEMBL4793897)
Affinity DataIC50: 94nMAssay Description:Inhibition of human TRKA at inactive state assessed as inhibition of substrate phosphorylation using fluorescently-labelled peptide as substrate by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50557927(CHEMBL4788009)
Affinity DataIC50: 102nMAssay Description:Inhibition of human TRKA at inactive state assessed as inhibition of substrate phosphorylation using fluorescently-labelled peptide as substrate by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557931(CHEMBL4739922)
Affinity DataIC50: 102nMAssay Description:Inhibition of human TRKA kinase domain by HTRF KinEASE biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557930(CHEMBL4740028)
Affinity DataIC50: 170nMAssay Description:Inhibition of human TRKA by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557929(CHEMBL4755144)
Affinity DataIC50: 178nMAssay Description:Inhibition of human TRKA kinase domain by HTRF KinEASE biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50557927(CHEMBL4788009)
Affinity DataIC50: 950nMAssay Description:Inhibition of human TRKA at active state assessed as inhibition of substrate phosphorylation using fluorescently-labelled peptide as substrate by cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557927(CHEMBL4788009)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of human TRKA at active state by kinetic based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557927(CHEMBL4788009)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human TRKA by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557931(CHEMBL4739922)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human TRKA by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557927(CHEMBL4788009)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human TRKB by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557929(CHEMBL4755144)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human TRKA at inactive state assessed as inhibition of substrate phosphorylation using fluorescently-labelled peptide as substrate by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50557929(CHEMBL4755144)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human TRKA at active state assessed as inhibition of substrate phosphorylation using fluorescently-labelled peptide as substrate by cal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBDNF/NT-3 growth factors receptor(Human)
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557930(CHEMBL4740028)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of human TRKB by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557928(CHEMBL4800240)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human TRKB by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557931(CHEMBL4739922)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human TRKB by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Zoetis

Curated by ChEMBL
LigandPNGBDBM50557929(CHEMBL4755144)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human TRKB by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557928(CHEMBL4800240)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human TRKA by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
LigandPNGBDBM50557929(CHEMBL4755144)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human TRKA by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)