Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50012011
TargetEpidermal growth factor receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553238(CHEMBL4750343)
Affinity DataIC50: 236nMAssay Description:Inhibition of EGFR (unknown origin) using Tyrosine 4 peptide and ATP as substrate incubated for 1 hr by Z'-lyte kinase assay based UV-VIS spectrophot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 240nMAssay Description:Inhibition of EGFR (unknown origin) using Tyrosine 4 peptide and ATP as substrate incubated for 1 hr by Z'-lyte kinase assay based UV-VIS spectrophot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553238(CHEMBL4750343)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK4/Cyclin D3 (unknown origin) using Rb protein as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553238(CHEMBL4750343)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin) using Rb protein as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553238(CHEMBL4750343)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) using Rb protein as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553238(CHEMBL4750343)
Affinity DataIC50: 500nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) using Ser/Thr 12 peptide as substrate incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553236(CHEMBL4793639)
Affinity DataIC50: 617nMAssay Description:Inhibition of EGFR (unknown origin) using Tyrosine 4 peptide and ATP as substrate incubated for 1 hr by Z'-lyte kinase assay based UV-VIS spectrophot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50553237(CHEMBL4795888)
Affinity DataIC50: 710nMAssay Description:Inhibition of EGFR (unknown origin) using Tyrosine 4 peptide and ATP as substrate incubated for 1 hr by Z'-lyte kinase assay based UV-VIS spectrophot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed