Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50012010
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50553227(CHEMBL4763124)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50553228(CHEMBL4786553)
Affinity DataEC50:  130nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50233672(CHEMBL4095478)
Affinity DataEC50:  270nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50553229(CHEMBL4778041)
Affinity DataEC50:  890nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50553230(CHEMBL4776148)
Affinity DataEC50:  560nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50553231(CHEMBL4791973)
Affinity DataEC50:  880nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50412718(CHEMBL509819)
Affinity DataEC50:  350nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50553232(CHEMBL4782345)
Affinity DataEC50:  73nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50553233(CHEMBL4798456)
Affinity DataEC50:  62nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50553234(CHEMBL4793975)
Affinity DataEC50:  84nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50553235(CHEMBL4764373)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50553231(CHEMBL4791973)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at PAR2 in HUVEC cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50553234(CHEMBL4793975)
Affinity DataEC50:  90nMAssay Description:Agonist activity at PAR2 in HUVEC cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50553227(CHEMBL4763124)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization preincubated for 2 hrs with LPS and 30 mins with cRG...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50553227(CHEMBL4763124)
Affinity DataEC50:  3.50E+3nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization preincubated for 2 hrs with LPS followed by compound...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Marquette University

Curated by ChEMBL
LigandPNGBDBM50553227(CHEMBL4763124)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization treated with cRGD for 30 mins prior to compound addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed