Compile Data Set for Download or QSAR
Report error Found 105 Enz. Inhib. hit(s) with all data for entry = 50015587
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587720(CHEMBL5195946)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of full length human recombinant HDAC6 incubated for 30 to 60 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587716(CHEMBL5188297)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant full length HDAC6 (unknown origin) using fluorophore conjugated substrate by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM417049(4-((6-chloro-3,4-dihydroquinolin-1(2H)-yl)methyl)-...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of full length human recombinant HDAC6 using RHKKAc-AMC fluorogenic peptide as substrate incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM110036(US8609678, 2-((2-chlorophenyl)(phenyl)amino)-N-(7-...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of HDAC6 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using RHKKAc-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50562487(CHEMBL4757504)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587722(CHEMBL5173000)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of full length human recombinant HDAC6 expressed in baculovirus infected Sf9 cells using RHKKAc fluorogenic peptide as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587716(CHEMBL5188297)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant full length HDAC1 (unknown origin) using fluorophore conjugated substrate by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50562491(CHEMBL4744710)
Affinity DataIC50: 12nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587723(CHEMBL5202641)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant HDAC6 using BML-AK511 as substrate incubated for 60 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587716(CHEMBL5188297)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant full length HDAC2 (unknown origin) using fluorophore conjugated substrate by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC6 (unknown origin) using RHKKAc fluorogenic peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587719(CHEMBL5172211)
Affinity DataIC50: 21nMAssay Description:Inhibition of HDAC6 (unknown origin) incubated for 30 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApoptosis regulator Bcl-2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataIC50: 23nMAssay Description:Inhibition of BCL-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587717(CHEMBL5194437)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant HDAC6 incubated for 45 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM110036(US8609678, 2-((2-chlorophenyl)(phenyl)amino)-N-(7-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of HDAC1 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM419603(US10464911, Example 31)
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant HDAC6 using BML-AK511 as substrate incubated for 60 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM110036(US8609678, 2-((2-chlorophenyl)(phenyl)amino)-N-(7-...)
Affinity DataIC50: 45nMAssay Description:Inhibition of HDAC2 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM110036(US8609678, 2-((2-chlorophenyl)(phenyl)amino)-N-(7-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of HDAC3 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 48nMAssay Description:Inhibition of HDAC2 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 51nMAssay Description:Inhibition of HDAC3 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587716(CHEMBL5188297)
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant full length HDAC3 (unknown origin) using fluorophore conjugated substrate by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM198121(HPOB)
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant HDAC6 incubated for 45 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587721(CHEMBL5206179)
Affinity DataIC50: 58nMAssay Description:Inhibition of human recombinant HDAC6 using ZMAL -Z-(Ac)Lys-AMC fluorogenic substrate incubated for 30 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 58nMAssay Description:Inhibition of HDAC1 (unknown origin) using FTS as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587720(CHEMBL5195946)
Affinity DataIC50: 64nMAssay Description:Inhibition of full length human recombinant HDAC3 incubated for 30 to 60 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) using RHKAcKAc-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 100nMAssay Description:Inhibition of HDAC8 (unknown origin) using MAZ-1675 as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587720(CHEMBL5195946)
Affinity DataIC50: 108nMAssay Description:Inhibition of full length human recombinant HDAC1 incubated for 30 to 60 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM110036(US8609678, 2-((2-chlorophenyl)(phenyl)amino)-N-(7-...)
Affinity DataIC50: 137nMAssay Description:Inhibition of HDAC8 (unknown origin) using MAZ-1675 as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587720(CHEMBL5195946)
Affinity DataIC50: 162nMAssay Description:Inhibition of full length human recombinant HDAC2 incubated for 30 to 60 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant HDAC1 (unknown origin) using RHKKAc-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50562491(CHEMBL4744710)
Affinity DataIC50: 319nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50562487(CHEMBL4757504)
Affinity DataIC50: 322nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587720(CHEMBL5195946)
Affinity DataIC50: 375nMAssay Description:Inhibition of full length human recombinant HDAC10 incubated for 30 to 60 mins by HDAC-Glo I/II assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587717(CHEMBL5194437)
Affinity DataIC50: 376nMAssay Description:Inhibition of human recombinant HDAC8 incubated for 45 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587719(CHEMBL5172211)
Affinity DataIC50: 388nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated for 30 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587717(CHEMBL5194437)
Affinity DataIC50: 677nMAssay Description:Inhibition of human recombinant HDAC10 incubated for 45 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587717(CHEMBL5194437)
Affinity DataIC50: 842nMAssay Description:Inhibition of human recombinant HDAC1 incubated for 45 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | US8748451, 6 | Tubastatin A | US92...)
Affinity DataIC50: 854nMAssay Description:Inhibition of HDAC8 (unknown origin) using RHKAcKAc fluorogenic-diacyl peptide as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587718(CHEMBL5185889)
Affinity DataIC50: 940nMAssay Description:Inhibition of recombinant HDAC5 (unknown origin) using acetyl-Lys(trifluoroacetyl)-AMC fluorogenic substrate by microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587717(CHEMBL5194437)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human recombinant HDAC7 incubated for 45 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50439674(US8609678, 2-(diphenylamino)-N-(7-(hydroxyamino)-7...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of HDAC7 (unknown origin) using MAZ-1675 as substrate preincubated for 10 mins followed by substrate addition by microtiter plate reader a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587716(CHEMBL5188297)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of recombinant full length HDAC8 (unknown origin) using fluorophore conjugated substrate by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM198121(HPOB)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant HDAC4 incubated for 45 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587717(CHEMBL5194437)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of human recombinant HDAC3 incubated for 45 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587717(CHEMBL5194437)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant HDAC4 incubated for 45 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587721(CHEMBL5206179)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant HDAC1 using ZMAL -Z-(Ac)Lys-AMC fluorogenic substrate incubated for 30 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587717(CHEMBL5194437)
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of human recombinant HDAC2 incubated for 45 mins by microplate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
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