Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50018507
LigandPNGBDBM50608972(CHEMBL5266334)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50608974(CHEMBL5288856)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50608973(CHEMBL4563588)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50035620(CHEMBL3338445)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50608971(CHEMBL5290355)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50608964(CHEMBL5271175)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM290889(US9579407, Example 00162 | 1-[2-fluoro-4- (tetrahy...)
Affinity DataIC50: 0.770nMAssay Description:Inhibition of PDE10A (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50496800(CHEMBL3218036)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to PDE10A in rat striatum homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50608970(CHEMBL5284754)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM290889(US9579407, Example 00162 | 1-[2-fluoro-4- (tetrahy...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDE10A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50365964(CHEMBL2070530 | CHEMBL1956235)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50520336(CHEMBL4470042)
Affinity DataIC50: 2nMAssay Description:Inhibition of human PDE10A (449 to 789 residues) expressed in Escherichia coli BL21(DE3) using cAMP as substrate incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM290889(US9579407, Example 00162 | 1-[2-fluoro-4- (tetrahy...)
Affinity DataKd:  4.70nMAssay Description:Binding affinity to PDE10A in rat brain nucleus accumbens by saturation binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM31604(methyl substituted pyrazole, 25)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50405611(CHEMBL5273419)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50608965(CHEMBL5276744)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50608975(CHEMBL5266740)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of PDE10A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM290889(US9579407, Example 00162 | 1-[2-fluoro-4- (tetrahy...)
Affinity DataKd:  12nMAssay Description:Binding affinity to PDE10A in rat brain caudate-putamen by saturation binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50003995(CHEMBL2180009)
Affinity DataIC50: 12nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50405608(CHEMBL5274332)
Affinity DataIC50: 22nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50608966(CHEMBL5277377)
Affinity DataIC50: 29nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50608962(CHEMBL5288169)
Affinity DataIC50: 44nMAssay Description:Inhibition of human PDE10A (449 to 789 residues) expressed in Escherichia coli BL21(DE3) using cAMP as substrate incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50608969(CHEMBL5280875)
Affinity DataIC50: 52nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50608968(CHEMBL5274729)
Affinity DataIC50: 112nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50035620(CHEMBL3338445)
Affinity DataIC50: 280nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50608963(CHEMBL563605)
Affinity DataIC50: 371nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
LigandPNGBDBM50608967(CHEMBL5287145)
Affinity DataIC50: 500nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed