Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50015600
TargetHistone deacetylase 3(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM425131(US10519177, Compound P-0014 | 4-[3[(2-chloro-6-flu...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC fluorogenic substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 11nMAssay Description:Inhibition of BRD3 BD1 (unknown origin) incubated for 30 mins by fluorescence based microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 11nMAssay Description:Inhibition of BRD2 BD2 (unknown origin) incubated for 30 mins by fluorescence based microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 11nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) incubated for 30 mins by fluorescence based microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain-containing protein 3(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 11nMAssay Description:Inhibition of BRD3 BD2 (unknown origin) incubated for 30 mins by fluorescence based microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain testis-specific protein(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 11nMAssay Description:Inhibition of BRDT BD2 (unknown origin) incubated for 30 mins by fluorescence based microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain testis-specific protein(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 11nMAssay Description:Inhibition of BRDT BD1 (unknown origin) incubated for 30 mins by fluorescence based microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 11nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) incubated for 30 mins by fluorescence based microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain-containing protein 2(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 11nMAssay Description:Inhibition of BRD2 BD1 (unknown origin) incubated for 30 mins by fluorescence based microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 11nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50569836(CHEMBL4850926)
Affinity DataIC50: 21nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated for 30 mins by fluorescence based microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587652(CHEMBL5198491)
Affinity DataIC50: 30nMAssay Description:Inhibition of BRD4 (unknown origin) incubated for 30 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587652(CHEMBL5198491)
Affinity DataIC50: 31nMAssay Description:Inhibition of HDAC (unknown origin) incubated for 30 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 43nMAssay Description:Inhibition of HDAC (unknown origin) incubated for 30 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 48nMAssay Description:Inhibition of BRD4 (unknown origin) incubated for 30 mins by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587760(CHEMBL5191199)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC fluorogenic substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587649(CHEMBL5197137)
Affinity DataIC50: 74nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) incubated for 30 mins by fluorescence based multimode microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 180nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587649(CHEMBL5197137)
Affinity DataIC50: 290nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated for 30 mins by fluorescence based multimode microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587649(CHEMBL5197137)
Affinity DataIC50: 720nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) incubated for 30 mins by fluorescence based multimode microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587650(CHEMBL5187070)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated for 30 mins by fluorescence based multimode microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587651(CHEMBL5179492)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) incubated for 30 mins by fluorescence based multimode microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587651(CHEMBL5179492)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) incubated for 30 mins by fluorescence based multimode microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587650(CHEMBL5187070)
Affinity DataIC50: 4.53E+3nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) incubated for 30 mins by fluorescence based multimode microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587650(CHEMBL5187070)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) incubated for 30 mins by fluorescence based multimode microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
The First Affiliated Hospital of Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50587651(CHEMBL5179492)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) incubated for 30 mins by fluorescence based multimode microtiter plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed