Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50013207
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universities of Shandong

Curated by ChEMBL
LigandPNGBDBM50563665(CHEMBL4785754)
Affinity DataIC50: 748nMAssay Description:Reversal of BCRP-mediated multidrug resistance in human KBV cells assessed as mitoxantrone IC50 at 10 uM after 72 hrs in presence of mitoxantrone by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universities of Shandong

Curated by ChEMBL
LigandPNGBDBM50563665(CHEMBL4785754)
Affinity DataIC50: 843nMAssay Description:Reversal of BCRP-mediated multidrug resistance in human KBV cells assessed as mitoxantrone IC50 at 5 uM after 72 hrs in presence of mitoxantrone by M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universities of Shandong

Curated by ChEMBL
LigandPNGBDBM50563666(CHEMBL4760910)
Affinity DataIC50: 1.01E+3nMAssay Description:Reversal of BCRP-mediated multidrug resistance in human KBV cells assessed as mitoxantrone IC50 at 10 uM after 72 hrs in presence of mitoxantrone by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universities of Shandong

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 1.19E+3nMAssay Description:Reversal of BCRP-mediated multidrug resistance in human KBV cells assessed as mitoxantrone IC50 at 10 uM after 72 hrs in presence of mitoxantrone by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Universities of Shandong

Curated by ChEMBL
LigandPNGBDBM50563666(CHEMBL4760910)
Affinity DataIC50: 1.46E+3nMAssay Description:Reversal of BCRP-mediated multidrug resistance in human KBV cells assessed as mitoxantrone IC50 at 5 uM after 72 hrs in presence of mitoxantrone by M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 2(Human)
Universities of Shandong

Curated by ChEMBL
LigandPNGBDBM50563665(CHEMBL4785754)
Affinity DataIC50: 5.00E+3nMAssay Description:Reversal of MRP2-mediated multidrug resistance in human KBV cells assessed as cisplatin IC50 at 10 uM after 72 hrs in presence of cisplatin by MTT as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 2(Human)
Universities of Shandong

Curated by ChEMBL
LigandPNGBDBM50563666(CHEMBL4760910)
Affinity DataIC50: 5.00E+3nMAssay Description:Reversal of MRP2-mediated multidrug resistance in human KBV cells assessed as cisplatin IC50 at 10 uM after 72 hrs in presence of cisplatin by MTT as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 2(Human)
Universities of Shandong

Curated by ChEMBL
LigandPNGBDBM81939(NSC_62969 | VERAPAMIL | CAS_52-53-9)
Affinity DataIC50: 5.00E+3nMAssay Description:Reversal of MRP2-mediated multidrug resistance in human KBV cells assessed as cisplatin IC50 at 10 uM after 72 hrs in presence of cisplatin by MTT as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 2(Human)
Universities of Shandong

Curated by ChEMBL
LigandPNGBDBM50563665(CHEMBL4785754)
Affinity DataIC50: 5.00E+3nMAssay Description:Reversal of MRP2-mediated multidrug resistance in human KBV cells assessed as cisplatin IC50 at 5 uM after 72 hrs in presence of cisplatin by MTT ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 2(Human)
Universities of Shandong

Curated by ChEMBL
LigandPNGBDBM50563666(CHEMBL4760910)
Affinity DataIC50: 5.00E+3nMAssay Description:Reversal of MRP2-mediated multidrug resistance in human KBV cells assessed as cisplatin IC50 at 5 uM after 72 hrs in presence of cisplatin by MTT ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed