Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50017377
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601453(CHEMBL5197549)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human wild type BTK using Poly(Glu4,Tyr1) and ATP as substrate measured after 2 hrs by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50558803(CHEMBL4793094)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of BTK (unknown origin) using Poly(Glu4,Tyr1) as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50558811(CHEMBL4790832)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of BTK (unknown origin) using Poly(Glu4,Tyr1) as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601460(CHEMBL5178356)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of BTK (unknown origin) incubated for 10 mins by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601461(CHEMBL5203118)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of BTK (unknown origin) using Poly(Glu4,Tyr1) as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601462(CHEMBL5200275)
Affinity DataIC50: 7nMAssay Description:Inhibition of BTK (unknown origin) using Poly(Glu4,Tyr1) as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50462909(CHEMBL4243975)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of BTK (unknown origin) incubated for 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601451(CHEMBL5172511)
Affinity DataIC50: 18nMAssay Description:Inhibition of BTK (unknown origin) incubated for 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50558812(CHEMBL4755698)
Affinity DataIC50: 22nMAssay Description:Inhibition of BTK (unknown origin) using Poly(Glu4,Tyr1) as substrate in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601456(CHEMBL5202915)
Affinity DataIC50: 27nMAssay Description:Inhibition of BTK (unknown origin) incubated for 40 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601461(CHEMBL5203118)
Affinity DataIC50: 29nMAssay Description:Inhibition EGFR (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601457(CHEMBL5206407)
Affinity DataIC50: 36nMAssay Description:Inhibition of BTK (unknown origin) incubated for 40 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601458(CHEMBL5197174)
Affinity DataIC50: 40nMAssay Description:Inhibition of BCR-ABL (unknown origin) using peptide GGEAIYAAPFKK as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601452(CHEMBL5185980)
Affinity DataIC50: 42nMAssay Description:Inhibition of BTK (unknown origin) incubated for 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601462(CHEMBL5200275)
Affinity DataIC50: 47nMAssay Description:Inhibition EGFR (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601454(CHEMBL5183488)
Affinity DataIC50: 75nMAssay Description:Inhibition of BTK (unknown origin) incubated for 40 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601455(CHEMBL5171731)
Affinity DataIC50: 82nMAssay Description:Inhibition of BTK (unknown origin) incubated for 40 mins by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601458(CHEMBL5197174)
Affinity DataIC50: 580nMAssay Description:Inhibition of BTK (unknown origin) using Poly(Glu4,Tyr1) as substrate in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601459(CHEMBL5174919)
Affinity DataIC50: 580nMAssay Description:Inhibition of BCR-ABL (unknown origin) using peptide GGEAIYAAPFKK as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50601459(CHEMBL5174919)
Affinity DataIC50: 2.65E+3nMAssay Description:Inhibition of BTK (unknown origin) using Poly(Glu4,Tyr1) as substrate in presence of ATP by radiometric kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Pla Strategic Support Force Medical Center

Curated by ChEMBL
LigandPNGBDBM50558812(CHEMBL4755698)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed