Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50035744
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023721(5-(4-Chloro-benzoylamino)-2-{4-[(2,4-diamino-pteri...)
Affinity DataIC50: 15nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 25nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023713(5-Benzoylamino-2-{4-[(2,4-diamino-pteridin-6-ylmet...)
Affinity DataIC50: 27nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023722(5-(4-Chloro-benzoylamino)-2-{4-[(2,4-diamino-pteri...)
Affinity DataIC50: 28nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023718(5-Acetylamino-2-{4-[(2,4-diamino-pteridin-6-ylmeth...)
Affinity DataIC50: 28nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023720(5-(3-Carboxy-propionylamino)-2-{4-[(2,4-diamino-pt...)
Affinity DataIC50: 32nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023712(5-Benzoylamino-2-{4-[(2,4-diamino-pteridin-6-ylmet...)
Affinity DataIC50: 34nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50367055(4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...)
Affinity DataIC50: 35nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023717(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...)
Affinity DataIC50: 45nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011320(CHEMBL18155 | N-(4-Carboxy-4-{4-[(2,4-diamino-pter...)
Affinity DataIC50: 52nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023716(5-Acetylamino-2-{4-[(2,4-diamino-pteridin-6-ylmeth...)
Affinity DataIC50: 53nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50023714(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-formyl-ami...)
Affinity DataIC50: 56nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50011885(CHEMBL280864 | 5-Amino-2-{4-[(2,4-diamino-pteridin...)
Affinity DataIC50: 72nMAssay Description:Inhibition of dihydrofolate reductase (DHFR) from murine leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed