Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50014439
TargetDCN1-like protein 1(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50576267(CHEMBL4876194)
Affinity DataEC50:  300nMAssay Description:Binding affinity to DCN1 in human HCC95 cells assessed as increase in thermal stability measured after 1 hr by CETSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50576267(CHEMBL4876194)
Affinity DataIC50: 110nMAssay Description:Inhibition of DCN1 (unknown origin) dependent cullin neddylation assessed as decrease in NEDD8 transfer from UBE2M to CUL2 using CUL2 as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetDCN1-like protein 1(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50245237(CHEMBL4074213 | US11116757, No. A7)
Affinity DataIC50: 170nMAssay Description:Inhibition of DCN1 (unknown origin) dependent cullin neddylation assessed as decrease in NEDD8 transfer from UBE2M to CUL2 using CUL2 as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)