Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50013960
TargetGlycogen synthase kinase-3 beta(Human)
Ohio University

Curated by ChEMBL
LigandPNGBDBM7262(NSC 705701 | BDBM84528 | alsterpaullone | 9-Nitrop...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human GSK-3beta incubated with substrate in presence of ATP measured by serial dilution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Ohio University

Curated by ChEMBL
LigandPNGBDBM7262(NSC 705701 | BDBM84528 | alsterpaullone | 9-Nitrop...)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human GSK-3beta preincubated for 3 hrs followed by ATP and substrate addition measured by serial dilution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Ohio University

Curated by ChEMBL
LigandPNGBDBM50571206(CHEMBL4861930)
Affinity DataIC50: 102nMAssay Description:Inhibition of human GSK-3beta preincubated for 3 hrs followed by ATP and substrate addition measured by serial dilution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Ohio University

Curated by ChEMBL
LigandPNGBDBM50166940(NP-031112 | NP-12 | Tideglusib | med.21724, Compou...)
Affinity DataIC50: 139nMAssay Description:Inhibition of human GSK-3beta preincubated for 3 hrs followed by ATP and substrate addition measured by serial dilution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Ohio University

Curated by ChEMBL
LigandPNGBDBM50571206(CHEMBL4861930)
Affinity DataIC50: 370nMAssay Description:Inhibition of human GSK-3beta incubated with substrate in presence of ATP measured by serial dilution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Ohio University

Curated by ChEMBL
LigandPNGBDBM50571206(CHEMBL4861930)
Affinity DataIC50: 370nMAssay Description:Inhibition of human wild type GSK-3beta incubated with substrate in presence of ATP measured by serial dilution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Ohio University

Curated by ChEMBL
LigandPNGBDBM50129131(CHEBI:83275 | Hypothemycin | US10434085, Compound ...)
Affinity DataIC50: 663nMAssay Description:Inhibition of human GSK-3beta preincubated for 3 hrs followed by ATP and substrate addition measured by serial dilution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Ohio University

Curated by ChEMBL
LigandPNGBDBM50166940(NP-031112 | NP-12 | Tideglusib | med.21724, Compou...)
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of human GSK-3beta incubated with substrate in presence of ATP measured by serial dilution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Ohio University

Curated by ChEMBL
LigandPNGBDBM50129131(CHEBI:83275 | Hypothemycin | US10434085, Compound ...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of human GSK-3beta incubated with substrate in presence of ATP measured by serial dilution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Ohio University

Curated by ChEMBL
LigandPNGBDBM50571206(CHEMBL4861930)
Affinity DataIC50: 1.21E+5nMAssay Description:Inhibition of human GSK-3beta C199A mutant incubated with substrate in presence of ATP measured by serial dilution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed