Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50014999
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50581791(CHEMBL5073221)
Affinity DataKi:  0.0320nMAssay Description:Inhibition of wild type HIV-1 protease assessed as initial inhibition constant by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCathepsin E(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50581791(CHEMBL5073221)
Affinity DataKi:  440nMAssay Description:Inhibition of human cathepsin E assessed as inhibition constant using ACC-GKPILFFRILK-(DNP)-(dR)-NH2 as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCathepsin D(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50581791(CHEMBL5073221)
Affinity DataKi:  620nMAssay Description:Inhibition of human cathepsin D assessed as inhibition constant using ACC-GKPILFFRILK-(DNP)-(dR)-NH2 as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRenin(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50581791(CHEMBL5073221)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of human renin assessed as inhibition constant using H-R-E(EDANS)-1HPFHLVIHT-K(DABCYL)-R-OH as susbtrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed