Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50015078
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50582559(CHEMBL5093894)
Affinity DataIC50: 10nMAssay Description:Inhibition of human c-SRC using poly [Glu:Tyr] as substrate incubated for 30 mins followed by 33P-ATP addition and measured after 2 hrs by liquid sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50582559(CHEMBL5093894)
Affinity DataIC50: 10nMAssay Description:Inhibition of human FGFR1 using KKKSPGEYVNIEFG as substrate incubated for 30 mins followed by 33P-ATP addition and measured after 2 hrs by liquid sci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50582559(CHEMBL5093894)
Affinity DataIC50: 10nMAssay Description:Inhibition of human FLT3 using EAIYAAPFAKKK as substrate incubated for 30 mins followed by 33P-ATP addition and measured after 2 hrs by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50582559(CHEMBL5093894)
Affinity DataIC50: 10nMAssay Description:Inhibition of human KDR/VEGFR2 using poly [Glu:Tyr] as substrate incubated for 30 mins followed by 33P-ATP addition and measured after 2 hrs by liqui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50582559(CHEMBL5093894)
Affinity DataIC50: 10nMAssay Description:Inhibition of human LYN using poly [Glu:Tyr] as substrate incubated for 30 mins followed by 33P-ATP addition and measured after 2 hrs by liquid scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50582559(CHEMBL5093894)
Affinity DataIC50: 10nMAssay Description:Inhibition of human PDGFRa using poly [Glu:Tyr] as substrate incubated for 30 mins followed by 33P-ATP addition and measured after 2 hrs by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50322535(3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-meth...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50582559(CHEMBL5093894)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of hERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed