Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50015630
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587908(CHEMBL5193790)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of ovine COX-2 colorimetric enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587909(CHEMBL5174073)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of ovine COX-2 colorimetric enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587913(CHEMBL5174387)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant COX-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 43nMAssay Description:Inhibition of ovine COX-2 colorimetric enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 90nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid as substrate measured after 2 mins by colorimetric enzyme immune assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587914(CHEMBL5200917)
Affinity DataIC50: 110nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid as substrate measured after 2 mins by colorimetric enzyme immune assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 160nMAssay Description:Inhibition of ovine COX-2 by colorimetric inhibitor screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587915(CHEMBL5196989)
Affinity DataIC50: 170nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid as substrate measured after 2 mins by colorimetric enzyme immune assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587910(CHEMBL5195593)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant EGFR (unknown origin) expressed in baculovirus incubated for 10 mins by europium-labeled antiphosphotyrosine/enhancement so...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCytochrome c oxidase subunit 2(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587916(CHEMBL5198027)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of ovine COX-2 by colorimetric inhibitor screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587912(CHEMBL5202840)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of ovine COX-1 preincubated for 10 mins followed by arachidonic acid addition for 2 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSeed linoleate 13S-lipoxygenase-1(Soybean)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587907(CHEMBL5175372)
Affinity DataIC50: 6.54E+4nMAssay Description:Inhibition of soybean LOX-1 using linoleic acid as substrate measured for 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCytochrome c oxidase subunit 2(Human)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587911(CHEMBL5183049)
Affinity DataKi:  9.46E+4nMAssay Description:Binding affinity to human recombinant COX-2 assessed as inhibition constant preincubated for 5 mins followed by arachidonic acid addition measured ev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Dpsr University

Curated by ChEMBL
LigandPNGBDBM50587912(CHEMBL5202840)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibition of human recombinant COX-2 preincubated for 10 mins followed by arachidonic acid addition for 2 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed