Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50017969
TargetBromodomain-containing protein 3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50606590(CHEMBL5218870)
Affinity DataKi:  131nMAssay Description:Binding affinity to recombinant human BRD3 bromodomain-1 (44 to 168 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as inhibition c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTranscriptional enhancer factor TEF-3(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50606588(CHEMBL5220985)
Affinity DataIC50: 510nMAssay Description:Inhibition of YAP binding to human TEAD4 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50606587(CHEMBL5219711)
Affinity DataKd:  3.30E+4nMAssay Description:Binding affinity to MDM2 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50606589(CHEMBL5219382)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of p300 (unknown origin) using [3H]-Ac-CoA as substrate preincubated for 15 mins followed by substrate addition and measured after 60 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed