Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50018642
TargetHistone deacetylase 6(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50202000(CHEMBL3973951)
Affinity DataIC50: 0.291nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610586(CHEMBL5280445)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50239858(CHEMBL4067006)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50247556(CHEMBL4104117)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50457751(CHEMBL4217087)
Affinity DataIC50: 8nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610587(CHEMBL5269169)
Affinity DataIC50: 13nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610585(CHEMBL5267651)
Affinity DataIC50: 28nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610591(CHEMBL5275589)
Affinity DataIC50: 40nMAssay Description:Inhibition of SMYD3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50475239(CHEMBL112234)
Affinity DataIC50: 72nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50134030(N,N'-(9-{[4-(dimethylamino)phenyl]amino}acridine-3...)
Affinity DataIC50: 95nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA topoisomerase 1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610584(CHEMBL5282818)
Affinity DataIC50: 278nMAssay Description:Inhibition of human topoisomerase 1 incubated for 2 hrs by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50430056(CHEMBL2336409 | SGI-1027)
Affinity DataIC50: 382nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610590(CHEMBL5285340)
Affinity DataIC50: 800nMAssay Description:Inhibition of C-terminal biotin-labelled human DNMT3A by multilabel plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610589(CHEMBL5276042)
Affinity DataIC50: 900nMAssay Description:Inhibition of DNMT3A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50594159(CHEMBL5177016)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of N-terminal His-tagged EZH2 in human PRC2 complex (2 to end residues) expressed in Sf9 cells using [3H]-SAM as substrate preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA topoisomerase 1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610582(CHEMBL488755 | TAS-103)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of topoisomerase 1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA topoisomerase 1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610583(CHEMBL5271591)
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of topoisomerase 1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA topoisomerase 1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50008935(CHEMBL84 | 10-Dimethylaminomethyl-4-ethyl-4,9-dihy...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human topoisomerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA topoisomerase 1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human topoisomerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610589(CHEMBL5276042)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of C-terminal biotin-labelled human DNMT3A by multilabel plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50457751(CHEMBL4217087)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of DNMT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3A(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610588(CHEMBL5269562)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human recombinant DNMT3A (214 to 912 residues)expressed in Sf9 insect cells using lambda DNA as substrate by scintillation/filter plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610589(CHEMBL5276042)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of his-tagged human DNMT1 by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610590(CHEMBL5285340)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of his-tagged human DNMT1 by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50610588(CHEMBL5269562)
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of human recombinant full-length N-terminal GST tagged DNMT1 (2 to 1632 residues) expressed in Sf9 insect cells using poly(dI-dC) as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed