Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50014006
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 12nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using RRRFRPASPLRGPPK as substrate by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50130725(SB-415286 | cid_4210951 | 3-(3-chloro-4-hydroxyphe...)
Affinity DataIC50: 54nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571752(CHEMBL4849247)
Affinity DataIC50: 71nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571739(CHEMBL4846517)
Affinity DataIC50: 144nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571750(CHEMBL4872945)
Affinity DataIC50: 200nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571743(CHEMBL4873680)
Affinity DataIC50: 400nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571731(CHEMBL4871399)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571733(CHEMBL4854952)
Affinity DataIC50: 5.15E+3nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571746(CHEMBL4845857)
Affinity DataIC50: 6.59E+3nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571735(CHEMBL4878234)
Affinity DataIC50: 7.62E+3nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571738(CHEMBL4869592)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571751(CHEMBL4873051)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571729(CHEMBL4859020)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571730(CHEMBL4875836)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571732(CHEMBL4854983)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571734(CHEMBL4878139)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571736(CHEMBL4848873)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571737(CHEMBL4870826)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571740(CHEMBL4863925)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571741(CHEMBL4856645)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571742(CHEMBL4868963)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571744(CHEMBL4875404)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571745(CHEMBL4866620)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571747(CHEMBL4861340)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571748(CHEMBL4861480)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571749(CHEMBL4860218)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM100152(cid_5359389 | SMR001233259 | HARMINE | 7-methoxy-1...)
Affinity DataIC50: 3.21E+4nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571728(CHEMBL4855547)
Affinity DataIC50: 8.97E+4nMAssay Description:Inhibition of human recombinant full length GST-tagged DYRK1A expressed in baculovirus infected cells incubated for 60 mins by TR-FRET based LanthaSc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed