Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50014530
TargetBeta-secretase 1(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM16034(N-[(1S,2R)-1-benzyl-3-(cyclopropylamino)-2-hydroxy...)
Affinity DataIC50: 15nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK fluorogenic peptide as substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50537951(Grifolic Acid)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK fluorogenic peptide as substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577137(CHEMBL4845912)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK fluorogenic peptide as substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK fluorogenic peptide as substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50458916(Grifolin)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK fluorogenic peptide as substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577137(CHEMBL4845912)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of self-induced aggregation amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of self-induced aggregation amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577139(CHEMBL4846858)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK fluorogenic peptide as substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577138(CHEMBL4847749)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK fluorogenic peptide as substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50537951(Grifolic Acid)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of self-induced aggregation amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577140(CHEMBL4871044)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK fluorogenic peptide as substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577138(CHEMBL4847749)
Affinity DataIC50: 4.07E+4nMAssay Description:Inhibition of self-induced aggregation amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577141(CHEMBL4877566)
Affinity DataIC50: 5.03E+4nMAssay Description:Inhibition of self-induced aggregation amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577139(CHEMBL4846858)
Affinity DataIC50: 5.14E+4nMAssay Description:Inhibition of self-induced aggregation amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577140(CHEMBL4871044)
Affinity DataIC50: 5.33E+4nMAssay Description:Inhibition of self-induced aggregation amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM16034(N-[(1S,2R)-1-benzyl-3-(cyclopropylamino)-2-hydroxy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of self-induced aggregation amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577141(CHEMBL4877566)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK fluorogenic peptide as substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50458916(Grifolin)
Affinity DataIC50: 1.49E+5nMAssay Description:Inhibition of self-induced aggregation amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed