Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50018251
Affinity DataEC50: 410nMAssay Description:Agonist activity at human TLR8 stably expressed in human HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SAP reporter gene based spectroph...More data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Antagonist activity at human TLR8 by Isothermal titration calorimetryMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKd: 21nMAssay Description:Antagonist activity at human TLR8 by Isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 220nMAssay Description:Antagonist activity at human TLR8 by Isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataEC50: 1.96E+3nMAssay Description:Agonist activity at human TLR8 (27 to 827 residues) stably expressed in human HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SAP reporter...More data for this Ligand-Target Pair
Affinity DataEC50: 2.48E+3nMAssay Description:Agonist activity at human TLR8 (27 to 827 residues) stably expressed in human HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SAP reporter...More data for this Ligand-Target Pair
Affinity DataEC50: 2.84E+4nMAssay Description:Agonist activity at human TLR8 (27 to 827 residues) stably expressed in human HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SAP reporter...More data for this Ligand-Target Pair
Affinity DataEC50: 1.13E+3nMAssay Description:Agonist activity at human TLR8 (27 to 827 residues) stably expressed in human HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SAP reporter...More data for this Ligand-Target Pair
Affinity DataEC50: 3.16E+3nMAssay Description:Agonist activity at human TLR8 (27 to 827 residues) stably expressed in human HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SAP reporter...More data for this Ligand-Target Pair
Affinity DataEC50: 3.23E+3nMAssay Description:Agonist activity at human TLR8 (27 to 827 residues) stably expressed in human HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SAP reporter...More data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Agonist activity at human TLR8 (27 to 827 residues) stably expressed in human HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SAP reporter...More data for this Ligand-Target Pair
Affinity DataEC50: 2.21E+3nMAssay Description:Agonist activity at human TLR7More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Antagonist activity at human TLR8 stably expressed in human HEK-Blue hTLR8 cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at human TLR8 stably expressed in human HEK-Blue hTLR8 cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human TLR9 expressed in HEK293 cells coexpressing firefly luciferase assessed as inhibition of CpGB-induced NFkappaB activatio...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human TLR9 expressed in HEK-Blue hTLR9 cells assessed as activation of NFkappaB incubated for 16 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human TLR9 expressed in HEK-Blue hTLR9 cells assessed as activation of NFkappaB incubated for 16 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Antagonist activity at human TLR8 stably expressed in human HEK-Blue hTLR8 cells incubated for 24 hrs by Quanti-Blue based SEAP assayMore data for this Ligand-Target Pair
