Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50014922
TargetALK tyrosine kinase receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 1.20nMAssay Description:Binding affinity to ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50581158(CHEMBL5084695)
Affinity DataIC50: 2.5nMAssay Description:Binding affinity to ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 4.10nMAssay Description:Binding affinity to ALK G1202R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50581158(CHEMBL5084695)
Affinity DataIC50: 6.60nMAssay Description:Binding affinity to ALK G1202R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed