Compile Data Set for Download or QSAR
Report error Found 108 Enz. Inhib. hit(s) with all data for entry = 50014927
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581204(CHEMBL5076637)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581191(CHEMBL5070876)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581204(CHEMBL5076637)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581180(CHEMBL5081214)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581203(CHEMBL5074599)
Affinity DataKi:  0.126nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581192(CHEMBL5091461)
Affinity DataKi:  0.126nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581209(CHEMBL4650755)
Affinity DataKi:  0.126nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581182(CHEMBL5080391)
Affinity DataIC50: 0.126nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581203(CHEMBL5074599)
Affinity DataKi:  0.126nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581185(CHEMBL5076558)
Affinity DataKi:  0.158nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581187(CHEMBL5077161)
Affinity DataKi:  0.158nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581209(CHEMBL4650755)
Affinity DataKi:  0.158nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M2 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581189(CHEMBL5075132)
Affinity DataKi:  0.158nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581183(CHEMBL5087564)
Affinity DataIC50: 0.158nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581202(CHEMBL5090464)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581203(CHEMBL5074599)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M2 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581190(CHEMBL5076266)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581193(CHEMBL5084383)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581184(CHEMBL5094110)
Affinity DataIC50: 0.251nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581199(CHEMBL5090179)
Affinity DataKi:  0.251nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581200(CHEMBL5084829)
Affinity DataKi:  0.316nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581185(CHEMBL5076558)
Affinity DataIC50: 0.316nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581201(CHEMBL5085717)
Affinity DataKi:  0.316nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581186(CHEMBL5088742)
Affinity DataKi:  0.316nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581188(CHEMBL5076680)
Affinity DataKi:  0.316nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581197(CHEMBL5077250)
Affinity DataIC50: 0.316nMAssay Description:Inhibition of human recombinant PDE4B2 assessed as reduction in cAMP level incubated for 2 hrs by LANCE Ultra cAMP TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50581181(CHEMBL5086895)
Affinity DataIC50: 0.316nMAssay Description:Inhibition of PDE4 in human U-937 cells assessed as reduction in cAMP level by LANCE cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581198(CHEMBL5086769)
Affinity DataKi:  0.316nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581185(CHEMBL5076558)
Affinity DataKi:  0.398nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581185(CHEMBL5076558)
Affinity DataKi:  0.398nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581183(CHEMBL5087564)
Affinity DataKi:  0.398nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581206(CHEMBL5076886)
Affinity DataKi:  0.501nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581192(CHEMBL5091461)
Affinity DataIC50: 0.501nMAssay Description:Inhibition of human recombinant PDE4B2 assessed as reduction in cAMP level incubated for 2 hrs by LANCE Ultra cAMP TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581206(CHEMBL5076886)
Affinity DataKi:  0.501nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581195(CHEMBL5085166)
Affinity DataKi:  0.501nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581184(CHEMBL5094110)
Affinity DataKi:  0.631nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581204(CHEMBL5076637)
Affinity DataIC50: 0.631nMAssay Description:Inhibition of human recombinant PDE4B2 assessed as reduction in cAMP level incubated for 2 hrs by LANCE Ultra cAMP TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581204(CHEMBL5076637)
Affinity DataIC50: 0.631nMAssay Description:Inhibition of human recombinant PDE4B2 assessed as reduction in cAMP level incubated for 2 hrs by LANCE Ultra cAMP TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581205(CHEMBL5077424)
Affinity DataKi:  0.631nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581195(CHEMBL5085166)
Affinity DataIC50: 0.631nMAssay Description:Inhibition of human recombinant PDE4B2 assessed as reduction in cAMP level incubated for 2 hrs by LANCE Ultra cAMP TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581205(CHEMBL5077424)
Affinity DataKi:  0.631nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581196(CHEMBL5086272)
Affinity DataIC50: 0.631nMAssay Description:Inhibition of human recombinant PDE4B2 assessed as reduction in cAMP level incubated for 2 hrs by LANCE Ultra cAMP TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581181(CHEMBL5086895)
Affinity DataKi:  0.631nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM325605(US9636336, Example 23 | US9636336, Example 86 | [(...)
Affinity DataIC50: 0.794nMAssay Description:Inhibition of human recombinant PDE4B2 assessed as reduction in cAMP level incubated for 2 hrs by LANCE Ultra cAMP TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581210(Ipratropium | Ipratropium cation | Ipratropium ion...)
Affinity DataKi:  0.794nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M2 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581210(Ipratropium | Ipratropium cation | Ipratropium ion...)
Affinity DataKi:  0.794nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581179(CHEMBL5078680)
Affinity DataKi:  0.794nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581196(CHEMBL5086272)
Affinity DataKi:  0.794nMAssay Description:Displacement of [3H]-N-methyl Scopolamine Chloride from human M3 receptor membranes incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM50581198(CHEMBL5086769)
Affinity DataIC50: 0.794nMAssay Description:Inhibition of human recombinant PDE4B2 assessed as reduction in cAMP level incubated for 2 hrs by LANCE Ultra cAMP TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Chiesi Farmaceutici

Curated by ChEMBL
LigandPNGBDBM325605(US9636336, Example 23 | US9636336, Example 86 | [(...)
Affinity DataIC50: 0.794nMAssay Description:Inhibition of human recombinant PDE4B2 assessed as reduction in cAMP level incubated for 2 hrs by LANCE Ultra cAMP TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
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