Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50015638
TargetSignal transducer and activator of transcription 3(Human)
Jinan Second People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50366601(CHEMBL4171066)
Affinity DataEC50:  870nMAssay Description:Inhibition of STAT3 phosphorylation in human MDA-MB-231 cells incubated for 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetArylsulfatase A(Human)
Jinan Second People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50251697(CHEMBL4093222)
Affinity DataKd:  2.10E+4nMAssay Description:Binding affinity to ARSA (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Jinan Second People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50587996(CHEMBL5203291)
Affinity DataIC50: 96nMAssay Description:Inhibition of human BuChE at 550 uM using butyrylthiocholine chloride as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetNAD(P)H dehydrogenase [quinone] 1(Human)
Jinan Second People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50587995(CHEMBL5181971)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of NQO1 in human HT-29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetArylsulfatase A(Human)
Jinan Second People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50251697(CHEMBL4093222)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of ARSA (unknown origin) using 4-methylumbelliferyl sulfate (4-MUS) as a substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed