Compile Data Set for Download or QSAR
Report error Found 59 Enz. Inhib. hit(s) with all data for entry = 50018396
TargetCollagenase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50386430(CHEMBL2047536)
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 0.410nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 0.670nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 0.790nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50063918((2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methyl...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of MMP-14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592900(CHEMBL5175770)
Affinity DataKi:  3nMAssay Description:Inhibition of human recombinant MMP-1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM13126(CHEMBL85030 | (2R)-2-[benzyl(4-methoxybenzene)sulf...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of MMP-13 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrilysin(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of MMP-7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592900(CHEMBL5175770)
Affinity DataKi:  4.40nMAssay Description:Inhibition of MMP-8 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  5nMAssay Description:Competitive inhibition of human MMP-9 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50388914(CHEMBL2063274 | US10357546, p-OH SB-3CT)
Affinity DataKi:  6nMAssay Description:Competitive inhibition of human MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM13126(CHEMBL85030 | (2R)-2-[benzyl(4-methoxybenzene)sulf...)
Affinity DataKi:  8nMAssay Description:Inhibition of recombinant human MMP-9 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50108168(BMS-275291 | Rebimastat | 2-[2-Mercapto-4-(3,4,4-t...)
Affinity DataIC50: 9nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50084661(Tanomastat | 4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-p...)
Affinity DataKi:  11nMAssay Description:Inhibition of MMP-2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50264809(Thiirane, 1 | Thiirane (deuterium), 1-d2 | CHEMBL4...)
Affinity DataKi:  14nMAssay Description:Competitive inhibition of human MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 14nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM13126(CHEMBL85030 | (2R)-2-[benzyl(4-methoxybenzene)sulf...)
Affinity DataKi:  20nMAssay Description:Inhibition of human recombinant MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50335495(4-(4-(thiiran-2-ylmethylsulfonyl)phenoxy)phenyl me...)
Affinity DataKi:  23nMAssay Description:Competitive inhibition of human MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrilysin(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50108168(BMS-275291 | Rebimastat | 2-[2-Mercapto-4-(3,4,4-t...)
Affinity DataIC50: 23nMAssay Description:Inhibition of MMP-7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50354624(CHEMBL1834422 | US9951035, ND-322 (2) | US10357546...)
Affinity DataKi:  24nMAssay Description:Competitive inhibition of human MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50108168(BMS-275291 | Rebimastat | 2-[2-Mercapto-4-(3,4,4-t...)
Affinity DataIC50: 27nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50082556(AG-3340 | 2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benz...)
Affinity DataKi:  30nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50082556(AG-3340 | 2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benz...)
Affinity DataKi:  30nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50082556(AG-3340 | 2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benz...)
Affinity DataKi:  30nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50082556(AG-3340 | 2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benz...)
Affinity DataKi:  30nMAssay Description:Inhibition of MMP-13 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM13126(CHEMBL85030 | (2R)-2-[benzyl(4-methoxybenzene)sulf...)
Affinity DataKi:  33nMAssay Description:Inhibition of human recombinant MMP-1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50108168(BMS-275291 | Rebimastat | 2-[2-Mercapto-4-(3,4,4-t...)
Affinity DataIC50: 39nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-14(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50108168(BMS-275291 | Rebimastat | 2-[2-Mercapto-4-(3,4,4-t...)
Affinity DataIC50: 40nMAssay Description:Inhibition of MMP-14 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM13126(CHEMBL85030 | (2R)-2-[benzyl(4-methoxybenzene)sulf...)
Affinity DataKi:  43nMAssay Description:Inhibition of human recombinant MMP-3 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592900(CHEMBL5175770)
Affinity DataKi:  59nMAssay Description:Inhibition of MMP-9 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50335500(4-(Thiiran-2-ylmethylsulfonyl)phenyl ethanesulfona...)
Affinity DataKi:  90nMAssay Description:Competitive inhibition of human MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50084661(Tanomastat | 4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-p...)
Affinity DataKi:  134nMAssay Description:Inhibition of MMP-3 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592900(CHEMBL5175770)
Affinity DataKi:  154nMAssay Description:Inhibition of MMP-2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50108168(BMS-275291 | Rebimastat | 2-[2-Mercapto-4-(3,4,4-t...)
Affinity DataIC50: 157nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50388914(CHEMBL2063274 | US10357546, p-OH SB-3CT)
Affinity DataKi:  160nMAssay Description:Competitive inhibition of human MMP-9 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50084661(Tanomastat | 4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-p...)
Affinity DataKi:  301nMAssay Description:Inhibition of MMP-9 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50546206(CHEMBL1409442)
Affinity DataKd:  320nMAssay Description:Binding affinity to MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50354627(CHEMBL1834420)
Affinity DataKi:  520nMAssay Description:Competitive inhibition of human MMP-2 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50592900(CHEMBL5175770)
Affinity DataKi:  527nMAssay Description:Inhibition of MMP-3 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50264809(Thiirane, 1 | Thiirane (deuterium), 1-d2 | CHEMBL4...)
Affinity DataKi:  600nMAssay Description:Competitive inhibition of human MMP-9 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50354624(CHEMBL1834422 | US9951035, ND-322 (2) | US10357546...)
Affinity DataKi:  870nMAssay Description:Competitive inhibition of human MMP-9 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50084661(Tanomastat | 4-(4'-Chloro-biphenyl-4-yl)-4-oxo-2-p...)
Affinity DataKi:  1.47E+3nMAssay Description:Inhibition of MMP-13 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50607979(CHEMBL5277375)
Affinity DataIC50: 2.89E+3nMAssay Description:Inhibition of HDAC-8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50607979(CHEMBL5277375)
Affinity DataIC50: 4.83E+3nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
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