Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50015640
TargetEchinoderm microtubule-associated protein-like 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588000(CHEMBL4875115)
Affinity DataEC50:  27nMAssay Description:Protac activity at CRBN/EML4-ALK in human NCI-H3122 cells assessed as induction of EML4-ALK fusion protein degradation incubated for 16 hrs by Wester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588003(CHEMBL4859551)
Affinity DataIC50: 290nMAssay Description:Binding affinity to ALK (unknown origin) using TK as substrate incubated for 1 hr in presence of ATP by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588002(CHEMBL3747525)
Affinity DataIC50: 320nMAssay Description:Binding affinity to ALK (unknown origin) using TK as substrate incubated for 1 hr in presence of ATP by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50362781(CHEMBL1738797 | US9126931, 366 | Alectinib | 12565...)
Affinity DataIC50: 1.03E+3nMAssay Description:Binding affinity to ALK (unknown origin) using TK as substrate incubated for 1 hr in presence of ATP by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588000(CHEMBL4875115)
Affinity DataIC50: 1.36E+4nMAssay Description:Binding affinity to ALK (unknown origin) using TK as substrate incubated for 1 hr in presence of ATP by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50588001(CHEMBL5188519)
Affinity DataIC50: 3.06E+4nMAssay Description:Binding affinity to ALK (unknown origin) using TK as substrate incubated for 1 hr in presence of ATP by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed