Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50015093
TargetSubstance-P receptor(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50220136(CHEMBL1471 | 5-(((2R,3S)-2-((R)-1-(3,5-bis(trifluo...)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at NK1R (unknown origin) in presence of endogenous SP ligand preincubated for 10 mins followed by 30 min incubation with antagoni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50582755(CHEMBL5083565)
Affinity DataKi:  22nMAssay Description:Displacement of [125I]SP from human NK1R expressed in U373 MG cells assessed as inhibitory constant incubated for 30 mins by radioligand binding assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50582755(CHEMBL5083565)
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]SP from human NK1R expressed in U373 MG cells incubated for 30 mins by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50582755(CHEMBL5083565)
Affinity DataIC50: 353nMAssay Description:Antagonist activity at NK1R (unknown origin) in presence of endogenous SP ligand preincubated for 10 mins followed by 30 min incubation with antagoni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50582756(CHEMBL5078626)
Affinity DataIC50: 833nMAssay Description:Antagonist activity at NK1R (unknown origin) in presence of endogenous SP ligand preincubated for 10 mins followed by 30 min incubation with antagoni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Universidad De Sevilla

Curated by ChEMBL
LigandPNGBDBM50582754(CHEMBL5074991)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at NK1R (unknown origin) in presence of endogenous SP ligand preincubated for 10 mins followed by 30 min incubation with antagoni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed