Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50018400
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM21724(3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(p...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608061(CHEMBL5279076)
Affinity DataEC50:  36nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608043(CHEMBL5290504)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608044(CHEMBL5283282)
Affinity DataEC50:  45nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608038(CHEMBL5269488)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608040(CHEMBL5269815)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608050(CHEMBL5286137)
Affinity DataEC50:  55nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608041(CHEMBL5279023)
Affinity DataEC50:  56nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608048(CHEMBL5282217)
Affinity DataEC50:  59nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608039(CHEMBL5265755)
Affinity DataEC50:  65nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608049(CHEMBL5283211)
Affinity DataEC50:  75nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608052(CHEMBL5273460)
Affinity DataEC50:  108nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608035(CHEMBL5276267)
Affinity DataEC50:  128nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608036(CHEMBL5284886)
Affinity DataEC50:  134nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608051(CHEMBL5287154)
Affinity DataEC50:  158nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608045(CHEMBL5277460)
Affinity DataEC50:  179nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608042(CHEMBL5291272)
Affinity DataEC50:  194nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608037(CHEMBL5265857)
Affinity DataEC50:  234nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608047(CHEMBL5288328)
Affinity DataEC50:  259nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM21675(6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...)
Affinity DataEC50:  324nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608058(CHEMBL5269487)
Affinity DataEC50:  347nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608060(CHEMBL5270392)
Affinity DataEC50:  440nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608056(CHEMBL5285416)
Affinity DataEC50:  523nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608053(CHEMBL5285493)
Affinity DataEC50:  728nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608059(CHEMBL5288893)
Affinity DataEC50:  970nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608054(CHEMBL5270924)
Affinity DataEC50:  1.34E+3nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608046(CHEMBL5268254)
Affinity DataEC50:  1.39E+3nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608057(CHEMBL5276283)
Affinity DataEC50:  1.83E+3nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608055(CHEMBL5271526)
Affinity DataEC50: >1.85E+3nMAssay Description:Agonist activity at human FXR expressed in human Huh-7 cells co-transfected with FXRE-Luc reporter plasmid assessed as receptor transactivation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM21675(6alpha-Ethyl-Chenodeoxycholic Acid | (4R)-4-[(1S,2...)
Affinity DataEC50:  3.40E+3nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-transfected with CRE-Luc reporter plasmid assessed as receptor transactivation incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608061(CHEMBL5279076)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-transfected with CRE-Luc reporter plasmid assessed as receptor transactivation incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50608044(CHEMBL5283282)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells co-transfected with CRE-Luc reporter plasmid assessed as receptor transactivation incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed