Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50014745
TargetInterleukin-1 receptor-associated kinase 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50373415(CHEMBL256713)
Affinity DataIC50: 23nMAssay Description:Inhibition of truncated human N-terminal GST-fusion tagged IRAK1 (194 to 712 residues) expressed in baculovirus expression system using FAM-labelled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50373415(CHEMBL256713)
Affinity DataIC50: 24nMAssay Description:Inhibition of full length human N-terminal GST-fusion tagged IRAK4 expressed in baculovirus expression system using FAM-labelled peptide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50579721(CHEMBL4798892)
Affinity DataIC50: 60nMAssay Description:Inhibition of truncated human N-terminal GST-fusion tagged IRAK1 (194 to 712 residues) expressed in baculovirus expression system using FAM-labelled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50579722(CHEMBL4762381)
Affinity DataIC50: 72nMAssay Description:Inhibition of truncated human N-terminal GST-fusion tagged IRAK1 (194 to 712 residues) expressed in baculovirus expression system using FAM-labelled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50579720(CHEMBL5083561)
Affinity DataIC50: 79nMAssay Description:Inhibition of truncated human N-terminal GST-fusion tagged IRAK1 (194 to 712 residues) expressed in baculovirus expression system using FAM-labelled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50579719(CHEMBL5075213)
Affinity DataIC50: 80nMAssay Description:Inhibition of truncated human N-terminal GST-fusion tagged IRAK1 (194 to 712 residues) expressed in baculovirus expression system using FAM-labelled ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50579721(CHEMBL4798892)
Affinity DataIC50: 260nMAssay Description:Inhibition of full length human N-terminal GST-fusion tagged IRAK4 expressed in baculovirus expression system using FAM-labelled peptide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50579720(CHEMBL5083561)
Affinity DataIC50: 320nMAssay Description:Inhibition of full length human N-terminal GST-fusion tagged IRAK4 expressed in baculovirus expression system using FAM-labelled peptide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50579719(CHEMBL5075213)
Affinity DataIC50: 368nMAssay Description:Inhibition of full length human N-terminal GST-fusion tagged IRAK4 expressed in baculovirus expression system using FAM-labelled peptide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50579722(CHEMBL4762381)
Affinity DataIC50: 443nMAssay Description:Inhibition of full length human N-terminal GST-fusion tagged IRAK4 expressed in baculovirus expression system using FAM-labelled peptide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
Targetvon Hippel-Lindau disease tumor suppressor(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50579722(CHEMBL4762381)
Affinity DataIC50: 1.07E+3nMAssay Description:Displacement of 5-FAM-labelled DEALA-HypYIPMDDDFQLRSF peptide from VHL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
Targetvon Hippel-Lindau disease tumor suppressor(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50579721(CHEMBL4798892)
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of 5-FAM-labelled DEALA-HypYIPMDDDFQLRSF peptide from VHL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
Targetvon Hippel-Lindau disease tumor suppressor(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50579719(CHEMBL5075213)
Affinity DataIC50: 1.65E+3nMAssay Description:Displacement of 5-FAM-labelled DEALA-HypYIPMDDDFQLRSF peptide from VHL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
Targetvon Hippel-Lindau disease tumor suppressor(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50579720(CHEMBL5083561)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of 5-FAM-labelled DEALA-HypYIPMDDDFQLRSF peptide from VHL (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed