Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50017413
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM552952(N-[2-[(3S)-3,4- dimethylpiperazin-1-yl]- 4-fluoro-...)
Affinity DataKd:  0.0600nMAssay Description:Binding affinity to N-terminal His-tagged and C-terminal Avi-tagged full length human WDR5 WIN site expressed in Escherichia coli measured upto 600 s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50601691(CHEMBL4116915)
Affinity DataIC50: 0.900nMAssay Description:Binding affinity to WDR5 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM200723(US9233086, 10L)
Affinity DataIC50: 2.40nMAssay Description:Binding affinity to WDR5 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM200712(US9233086, 10A)
Affinity DataIC50: 2.90nMAssay Description:Binding affinity to WDR5 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50601692(CHEMBL5172154)
Affinity DataIC50: 7.40nMAssay Description:Binding affinity to WDR5 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574672(CHEMBL4861912)
Affinity DataIC50: 10nMAssay Description:Binding affinity to WDR5 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50601692(CHEMBL5172154)
Affinity DataKd:  14nMAssay Description:Binding affinity to WDR5 (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50601695(CHEMBL5179283)
Affinity DataIC50: 17nMAssay Description:Binding affinity to WDR5 (unknown origin) WIN site using 10mer-Thr-FAM probe incubated for 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50601694(CHEMBL5183439)
Affinity DataIC50: 20nMAssay Description:Inhibition of MLL1 (unknown origin) histone methyltransferase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50601693(CHEMBL5198658)
Affinity DataIC50: 26nMAssay Description:Binding affinity to WDR5 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50581147(CHEMBL5094242)
Affinity DataIC50: 29nMAssay Description:Binding affinity to WDR5 (unknown origin) fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase 2A(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50601692(CHEMBL5172154)
Affinity DataIC50: 190nMAssay Description:Inhibition of MLL1 (unknown origin) histone methyltransferase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetWD repeat-containing protein 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50428254(CHEMBL1609857)
Affinity DataKd:  4.00E+3nMAssay Description:Binding affinity to human WDR5 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)