Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50013519
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50567001(CHEMBL4873898)
Affinity DataKd:  1.5nMAssay Description:Binding affinity to human His-tagged MAGL assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566987(CHEMBL4854370)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566988(CHEMBL4860900)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566989(CHEMBL4872007)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566999(CHEMBL4868762)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566984(CHEMBL4870918)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50567002(CHEMBL4861633)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50567003(CHEMBL4866307)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566990(CHEMBL4871941)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50567000(CHEMBL4847556)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566998(CHEMBL4865443)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50567005(CHEMBL4845748)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50567001(CHEMBL4873898)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50567004(CHEMBL4854074)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566982(CHEMBL4846513)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566997(CHEMBL4862009)
Affinity DataIC50: 7nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50567006(CHEMBL4856861)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566991(CHEMBL4872359)
Affinity DataIC50: 11nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566981(CHEMBL4850390)
Affinity DataIC50: 11nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50567001(CHEMBL4873898)
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566972(CHEMBL4870749)
Affinity DataIC50: 15nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566996(CHEMBL4847831)
Affinity DataIC50: 18nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566973(CHEMBL4872139)
Affinity DataIC50: 26nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566974(CHEMBL4855733)
Affinity DataIC50: 27nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566994(CHEMBL4862447)
Affinity DataIC50: 29nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566975(CHEMBL4867138)
Affinity DataIC50: 32nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566995(CHEMBL4870417)
Affinity DataIC50: 34nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566993(CHEMBL4874410)
Affinity DataIC50: 38nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566980(CHEMBL4867695)
Affinity DataIC50: 38nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566992(CHEMBL4854188)
Affinity DataIC50: 58nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566977(CHEMBL4849041)
Affinity DataIC50: 63nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566985(CHEMBL4859927)
Affinity DataIC50: 73nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566978(CHEMBL4870350)
Affinity DataIC50: 190nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566979(CHEMBL4876184)
Affinity DataIC50: 590nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566983(CHEMBL4864582)
Affinity DataIC50: 890nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566976(CHEMBL4873118)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM60622(BDBM50300355 | US9133148, A | US11753371, Compound...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50567001(CHEMBL4873898)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoacylglycerol lipase ABHD6(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50567001(CHEMBL4873898)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABHD6 expressed in Expi293 cells using p-nitrophenyl acetate as substrate incubated for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50566986(CHEMBL4869950)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human His-tagged MAGL assessed as formation of arachidonic acid using 2-acylglycerol incubated for 10 mins by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed