Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50018285
TargetTyrosine-protein kinase JAK2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50410792(CHEMBL5272587)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human JAK2 using biotin as a substrate preincubated for 5 mins followed by substrate addition incubated for 30 mins in presence of ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50410791(CHEMBL5279689)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human JAK2 using biotin as a substrate preincubated for 5 mins followed by substrate addition incubated for 30 mins in presence of ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50410794(CHEMBL5279426)
Affinity DataIC50: 8nMAssay Description:Inhibition of human JAK2 using biotin as a substrate preincubated for 5 mins followed by substrate addition incubated for 30 mins in presence of ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50410792(CHEMBL5272587)
Affinity DataIC50: 8nMAssay Description:Inhibition of human BTK using biotin as a substrate preincubated for 5 mins followed by substrate addition incubated for 30 mins in presence of ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50410793(CHEMBL5282475)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human JAK2 using biotin as a substrate preincubated for 5 mins followed by substrate addition incubated for 30 mins in presence of ATP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50249029(CHEMBL4088300)
Affinity DataIC50: 10nMAssay Description:Inhibition of human RET kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50410795(CHEMBL5288191)
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50410790(CHEMBL5281486)
Affinity DataIC50: 4.18E+3nMAssay Description:Inhibition of human EGFR in presence of ATP by Kinase-Glo Plus luminescence kinase assay kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50410795(CHEMBL5288191)
Affinity DataIC50: 5.83E+3nMAssay Description:Inhibition of EGFR (unknown origin) by EGFR Kinase Assay Kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed