Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50015517
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587201(CHEMBL5094074)
Affinity DataEC50:  3.30nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587206(CHEMBL5076308)
Affinity DataEC50:  4.20nMAssay Description:Activation of human GCCR expressed in human CHO-K1 cell lines assessed as intracellular cAMP generation incubated for 30 mins measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587204(CHEMBL5070843)
Affinity DataEC50:  1.90nMAssay Description:Activation of human GCCR expressed in human CHO-K1 cell lines assessed as intracellular cAMP generation incubated for 30 mins measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587203(CHEMBL5088610)
Affinity DataEC50:  0.640nMAssay Description:Activation of human GCCR expressed in human CHO-K1 cell lines assessed as intracellular cAMP generation incubated for 30 mins measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587202(CHEMBL5090987)
Affinity DataEC50:  0.420nMAssay Description:Activation of human GCCR expressed in human CHO-K1 cell lines assessed as intracellular cAMP generation incubated for 30 mins measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587201(CHEMBL5094074)
Affinity DataEC50:  1.10nMAssay Description:Activation of human GCCR expressed in human CHO-K1 cell lines assessed as intracellular cAMP generation incubated for 30 mins measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587200(CHEMBL5074740)
Affinity DataEC50:  0.900nMAssay Description:Activation of human GCCR expressed in human CHO-K1 cell lines assessed as intracellular cAMP generation incubated for 30 mins measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587189(CHEMBL5091611)
Affinity DataEC50:  0.400nMAssay Description:Activation of human GCCR expressed in human CHO-K1 cell lines assessed as intracellular cAMP generation incubated for 30 mins measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587188(CHEMBL5080959)
Affinity DataEC50:  0.0400nMAssay Description:Activation of human GCCR expressed in human CHO-K1 cell lines assessed as intracellular cAMP generation incubated for 30 mins measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50266693(CHEBI:5391 | Glucagen Hypokit | Glucagon | Glucago...)
Affinity DataEC50:  0.0200nMAssay Description:Activation of human GCCR expressed in human CHO-K1 cell lines assessed as intracellular cAMP generation incubated for 30 mins measured by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587206(CHEMBL5076308)
Affinity DataEC50:  13nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587205(CHEMBL5089850)
Affinity DataEC50:  0nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587204(CHEMBL5070843)
Affinity DataEC50:  78nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587203(CHEMBL5088610)
Affinity DataEC50:  1.5nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587202(CHEMBL5090987)
Affinity DataEC50:  0.860nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587187(CHEMBL5093620)
Affinity DataEC50:  0.460nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587200(CHEMBL5074740)
Affinity DataEC50:  4.40nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587199(CHEMBL5077808)
Affinity DataEC50: >1.00E+3nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587198(CHEMBL5087633)
Affinity DataEC50: >1.00E+3nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587197(CHEMBL5079335)
Affinity DataEC50: >1.00E+3nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587196(CHEMBL5071539)
Affinity DataEC50: >1.00E+3nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587195(CHEMBL5081464)
Affinity DataEC50: >1.00E+3nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587194(CHEMBL5094483)
Affinity DataEC50: >1.00E+3nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587193(CHEMBL5089706)
Affinity DataEC50: >1.00E+3nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587192(CHEMBL5082974)
Affinity DataEC50: >1.00E+3nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587191(CHEMBL5091667)
Affinity DataEC50: >1.00E+3nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587190(CHEMBL5078729)
Affinity DataEC50: >1.00E+3nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587189(CHEMBL5091611)
Affinity DataEC50:  0.860nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50587188(CHEMBL5080959)
Affinity DataEC50:  0.280nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
University of South Florida

Curated by ChEMBL
LigandPNGBDBM50266693(CHEBI:5391 | Glucagen Hypokit | Glucagon | Glucago...)
Affinity DataEC50:  0.0300nMAssay Description:Activation of human GCCR expressed in human HEK293 cells assessed as luminescence signal incubated for 16 hrs at 37C measured by CRE-driven luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed