Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50015025
TargetAcetylcholinesterase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582079(CHEMBL5091959)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582080(CHEMBL5089279)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582081(CHEMBL5087842)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582082(CHEMBL5084050)
Affinity DataIC50: 6nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582084(CHEMBL5085880)
Affinity DataIC50: 13nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582083(CHEMBL5084158)
Affinity DataIC50: 15nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582078(CHEMBL5089868)
Affinity DataIC50: 18nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582085(CHEMBL5092574)
Affinity DataIC50: 29nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 43nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582086(CHEMBL5081945)
Affinity DataIC50: 66nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 147nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582079(CHEMBL5091959)
Affinity DataIC50: 200nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 237nMAssay Description:Inhibition of rat cortex AChE using acetylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarboxylic ester hydrolase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582080(CHEMBL5089279)
Affinity DataIC50: 347nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582078(CHEMBL5089868)
Affinity DataIC50: 401nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582081(CHEMBL5087842)
Affinity DataIC50: 503nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582082(CHEMBL5084050)
Affinity DataIC50: 574nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582083(CHEMBL5084158)
Affinity DataIC50: 893nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582085(CHEMBL5092574)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582084(CHEMBL5085880)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582084(CHEMBL5085880)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582078(CHEMBL5089868)
Affinity DataIC50: 2.41E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582085(CHEMBL5092574)
Affinity DataIC50: 2.76E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582086(CHEMBL5081945)
Affinity DataIC50: 2.77E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582086(CHEMBL5081945)
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582083(CHEMBL5084158)
Affinity DataIC50: 6.36E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582081(CHEMBL5087842)
Affinity DataIC50: 7.66E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582080(CHEMBL5089279)
Affinity DataIC50: 8.07E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 8.72E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582079(CHEMBL5091959)
Affinity DataIC50: 8.98E+3nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50582082(CHEMBL5084050)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of rat serum BChE using butyrylthiocholine iodide as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
The Hong Kong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of hERG expressed in CHO-K1 cells assessed as reduction in thallium influx incubated for 30 minutes by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed