Compile Data Set for Download or QSAR
Report error Found 118 Enz. Inhib. hit(s) with all data for entry = 50016838
LigandPNGBDBM50263263(CHEMBL4073443)
Affinity DataIC50: 1nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50263263(CHEMBL4073443)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Ser 209 phosphorylation of eIF4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM297345(US10112955, Example 12 | N-(6-((1-oxoisoindolin-5-...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Mnk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597685(CHEMBL5181488)
Affinity DataIC50: 2nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50263263(CHEMBL4073443)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of Mnk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597686(CHEMBL5183975)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597685(CHEMBL5181488)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Mnk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597687(CHEMBL5180948)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597686(CHEMBL5183975)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Mnk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597687(CHEMBL5180948)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of Mnk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597686(CHEMBL5183975)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of phosphorylation of eIF4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597682(CHEMBL5206647)
Affinity DataIC50: 4nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597684(CHEMBL5203720)
Affinity DataIC50: 4nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597668(CHEMBL5196282)
Affinity DataIC50: 4nMAssay Description:Inhibition of Mnk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597668(CHEMBL5196282)
Affinity DataIC50: 5nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597669(CHEMBL5204789)
Affinity DataIC50: 5nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597669(CHEMBL5204789)
Affinity DataIC50: 5nMAssay Description:Inhibition of Mnk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597684(CHEMBL5203720)
Affinity DataIC50: 5nMAssay Description:Inhibition of Mnk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM297345(US10112955, Example 12 | N-(6-((1-oxoisoindolin-5-...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597670(CHEMBL5176495)
Affinity DataIC50: 6nMAssay Description:Inhibition of Mnk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50263263(CHEMBL4073443)
Affinity DataIC50: 6nMAssay Description:Inhibition of phosphorylation of eIF4E (unknown origin) in HCT-116 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597682(CHEMBL5206647)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of Mnk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597683(CHEMBL5171562)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597684(CHEMBL5203720)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of phosphorylation of eIF4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597685(CHEMBL5181488)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of phosphorylation of eIF4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597670(CHEMBL5176495)
Affinity DataIC50: 8nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
A*Star

Curated by ChEMBL
LigandPNGBDBM400813(QL-X-138 | US10000483, Compound II-6)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of FLAG-tagged BTK (unknown origin) transfected into HEK293T cells incubated for 30 mins followed by ATP addition measured after 20 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597683(CHEMBL5171562)
Affinity DataIC50: 10nMAssay Description:Inhibition of Mnk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597676(CHEMBL5196084)
Affinity DataIC50: 13nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597676(CHEMBL5196084)
Affinity DataIC50: 13nMAssay Description:Inhibition of Mnk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597682(CHEMBL5206647)
Affinity DataIC50: 16nMAssay Description:Inhibition of phosphorylation of eIF4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50562615(CHEMBL4764756)
Affinity DataIC50: 18nMAssay Description:Inhibition of Mnk1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597673(CHEMBL5175341)
Affinity DataIC50: 20nMAssay Description:Inhibition of eIF4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597674(CHEMBL5187414)
Affinity DataIC50: 20nMAssay Description:Inhibition of eIF4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597675(CHEMBL5184155)
Affinity DataIC50: 20nMAssay Description:Inhibition of eIF4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597692(CHEMBL5181172)
Affinity DataIC50: 21nMAssay Description:Inhibition of inactive form of MNK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597672(CHEMBL5195560)
Affinity DataIC50: 25nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597676(CHEMBL5196084)
Affinity DataIC50: 25nMAssay Description:Inhibition of eIF4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597679(CHEMBL5195407)
Affinity DataIC50: 25nMAssay Description:Inhibition of phosphorylation of eIF4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM400813(QL-X-138 | US10000483, Compound II-6)
Affinity DataIC50: 26nMAssay Description:Inhibition of FLAG-tagged Mnk2 (unknown origin) transfected into HEK293 cells incubated for 30 mins followed by ATP addition measured after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597674(CHEMBL5187414)
Affinity DataIC50: 32nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597675(CHEMBL5184155)
Affinity DataIC50: 32nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597678(CHEMBL5183411)
Affinity DataIC50: 32nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597679(CHEMBL5195407)
Affinity DataIC50: 32nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597680(CHEMBL5205835)
Affinity DataIC50: 32nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597672(CHEMBL5195560)
Affinity DataIC50: 32nMAssay Description:Inhibition of eIF4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597683(CHEMBL5171562)
Affinity DataIC50: 32nMAssay Description:Inhibition of phosphorylation of eIF4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50597687(CHEMBL5180948)
Affinity DataIC50: 32nMAssay Description:Inhibition of phosphorylation of eIF4E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
LigandPNGBDBM50562615(CHEMBL4764756)
Affinity DataIC50: 35nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50256734((-)-Cercosporamide | CHEMBL475816)
Affinity DataIC50: 38nMAssay Description:Inhibition of Mnk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Displayed 1 to 50 (of 118 total ) | Next | Last >>
Jump to: