Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50018772
TargetVasopressin V1a receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50546436(CHEMBL4799793)
Affinity DataKi:  0.800nMAssay Description:Antagonist activity against human V1A receptor expressed in human 1321N1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM20557(N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...)
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at rat TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVasopressin V1a receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50546428(CHEMBL4778839)
Affinity DataKi:  1.40nMAssay Description:Antagonist activity against human V1A receptor expressed in human 1321N1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM20581(N-{4-[(6-{4-[(1R)-1-(4-fluorophenyl)ethyl]piperazi...)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at rat TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVasopressin V1a receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612387(CHEMBL5283016)
Affinity DataKi:  14nMAssay Description:Antagonist activity against human V1A receptor expressed in human 1321N1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM20561(N-[4-({6-[4-(trifluoromethyl)cyclohex-1-en-1-yl]py...)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at rat TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50132080(CHEMBL112065 | CHEMBL129483 | Biphenyl-4-carboxyli...)
Affinity DataIC50: 42nMAssay Description:Inhibition of hERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBeta-1 adrenergic receptor(Rat)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50036835(Dichloroisoproterenol,(+/-) | CHEMBL30816 | 1-(3,4...)
Affinity DataKi:  51nMAssay Description:Binding affinity to rat brain membrane adrenergic beta-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50385503(CHEMBL2040554)
Affinity DataKi:  84nMAssay Description:Inhibition of Influenza A virus N-terminal domain of PA endonuclease by fluorescence polarization methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPolymerase acidic protein(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612374(CHEMBL5286364)
Affinity DataKi:  90nMAssay Description:Inhibition of Influenza A virus N-terminal domain of PA endonuclease by fluorescence polarization methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Bovine)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50036835(Dichloroisoproterenol,(+/-) | CHEMBL30816 | 1-(3,4...)
Affinity DataKi:  140nMAssay Description:Binding affinity to bovine lung membrane adrenergic beta-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVasopressin V1a receptor(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612388(CHEMBL5283584)
Affinity DataKi:  140nMAssay Description:Antagonist activity against human V1A receptor expressed in human 1321N1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612384(CHEMBL5281608)
Affinity DataIC50: 170nMAssay Description:Inhibition of hERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM20563(N-[4-({6-[4-(trifluoromethyl)piperidin-1-yl]pyrimi...)
Affinity DataIC50: 330nMAssay Description:Antagonist activity at rat TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM20562(N-[4-({6-[4-(trifluoromethyl)cyclohexyl]pyrimidin-...)
Affinity DataIC50: 350nMAssay Description:Antagonist activity at rat TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 370nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM20569(N-[4-({6-[4-(2,2,2-trifluoroethyl)piperazin-1-yl]p...)
Affinity DataIC50: 380nMAssay Description:Antagonist activity at rat TRPV1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBeta-1 adrenergic receptor(Rat)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50036840(Propionaldehyde O-(3-tert-butylamino-2-hydroxy-pro...)
Affinity DataKi:  500nMAssay Description:Binding affinity to rat brain membrane adrenergic beta-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Bovine)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50036841(3-tert-Butylamino-2-hydroxy-propionaldehyde O-ethy...)
Affinity DataKi:  850nMAssay Description:Binding affinity to bovine lung membrane adrenergic beta-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBeta-1 adrenergic receptor(Rat)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50036841(3-tert-Butylamino-2-hydroxy-propionaldehyde O-ethy...)
Affinity DataKi:  850nMAssay Description:Binding affinity to rat brain membrane adrenergic beta-1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612379(CHEMBL5281225)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612380(CHEMBL5271953)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612377(CHEMBL5273946)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612378(CHEMBL5282860)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612383(CHEMBL5266376)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612381(CHEMBL5279557)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612382(CHEMBL5269948)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612375(CHEMBL5287588)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612376(CHEMBL5275489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetBeta-2 adrenergic receptor(Bovine)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50036840(Propionaldehyde O-(3-tert-butylamino-2-hydroxy-pro...)
Affinity DataKi:  1.26E+3nMAssay Description:Binding affinity to bovine lung membrane adrenergic beta-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612384(CHEMBL5281608)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50589218(CHEMBL5200108)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612385(CHEMBL5289407)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612386(CHEMBL115933)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50415442(CHEMBL598609)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50132080(CHEMBL112065 | CHEMBL129483 | Biphenyl-4-carboxyli...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50052256(3-[amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-ca...)
Affinity DataIC50: 2.50E+4nMAssay Description:Antagonist activity at mGluR1alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612385(CHEMBL5289407)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50612386(CHEMBL115933)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50415442(CHEMBL598609)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50589218(CHEMBL5200108)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50053588(4-((S)-Amino-carboxy-methyl)-benzoic acid | CHEMBL...)
Affinity DataIC50: 6.50E+4nMAssay Description:Antagonist activity at mGluR1alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Biocon-Bristol Myers Squibb Research and Development Centre

Curated by ChEMBL
LigandPNGBDBM50400857(CHEMBL2204334)
Affinity DataIC50: 6.89E+4nMAssay Description:Antagonist activity at mGluR1alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed