Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50035636
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 20nMAssay Description:Compound was tested for its inhibitory concentration to inhibit the enzyme Dihydro Folate Reductase (DHFR) from murine L1210 leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50367055(4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...)
Affinity DataIC50: 20nMAssay Description:Compound was tested for its inhibitory concentration to inhibit the enzyme Dihydro Folate Reductase (DHFR) from murine L1210 leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50023896(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-ami...)
Affinity DataIC50: 31nMAssay Description:Compound was tested for its inhibitory concentration to inhibit the enzyme Dihydro Folate Reductase (DHFR) from murine L1210 leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50023890(4-(Benzo[1,3]dioxol-5-ylcarbamoyl)-2-{4-[(2,4-diam...)
Affinity DataIC50: 42nMAssay Description:Compound was tested for its inhibitory concentration to inhibit the enzyme Dihydro Folate Reductase (DHFR) from murine L1210 leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50023897(4-tert-Butylcarbamoyl-2-{4-[(2,4-diamino-pteridin-...)
Affinity DataIC50: 44nMAssay Description:Compound was tested for its inhibitory concentration to inhibit the enzyme Dihydro Folate Reductase (DHFR) from murine L1210 leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50023898(4-(Benzo[1,3]dioxol-5-ylcarbamoyl)-2-{4-[(2,4-diam...)
Affinity DataIC50: 45nMAssay Description:Compound was tested for its inhibitory concentration to inhibit the enzyme Dihydro Folate Reductase (DHFR) from murine L1210 leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50023899(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...)
Affinity DataIC50: 57nMAssay Description:Compound was tested for its inhibitory concentration to inhibit the enzyme Dihydro Folate Reductase (DHFR) from murine L1210 leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50023894(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...)
Affinity DataIC50: 60nMAssay Description:Compound was tested for its inhibitory concentration to inhibit the enzyme Dihydro Folate Reductase (DHFR) from murine L1210 leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50023891(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...)
Affinity DataIC50: 80nMAssay Description:Compound was tested for its inhibitory concentration to inhibit the enzyme Dihydro Folate Reductase (DHFR) from murine L1210 leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50023895(4-Benzylcarbamoyl-2-{4-[(2,4-diamino-pteridin-6-yl...)
Affinity DataIC50: 87nMAssay Description:Compound was tested for its inhibitory concentration to inhibit the enzyme Dihydro Folate Reductase (DHFR) from murine L1210 leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50023893(4-(Adamantan-1-ylcarbamoyl)-2-{4-[(2,4-diamino-pte...)
Affinity DataIC50: 100nMAssay Description:Compound was tested for its inhibitory concentration to inhibit the enzyme Dihydro Folate Reductase (DHFR) from murine L1210 leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50023892(2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-amino]-ben...)
Affinity DataIC50: 130nMAssay Description:Compound was tested for its inhibitory concentration to inhibit the enzyme Dihydro Folate Reductase (DHFR) from murine L1210 leukemia cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed