Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50017069
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 23nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599546(CHEMBL5170796)
Affinity DataIC50: 190nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599545(CHEMBL5176010)
Affinity DataIC50: 280nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 340nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM18678(CHEMBL63560 | (2R)-N-[4-cyano-3-(trifluoromethyl)p...)
Affinity DataIC50: 350nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599536(CHEMBL5173941)
Affinity DataIC50: 390nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599533(CHEMBL5204177)
Affinity DataIC50: 390nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 450nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599539(CHEMBL5169631)
Affinity DataIC50: 750nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599537(CHEMBL5180580)
Affinity DataIC50: 980nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599536(CHEMBL5173941)
Affinity DataIC50: 990nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599545(CHEMBL5176010)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599534(CHEMBL5169570)
Affinity DataIC50: 1.17E+3nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599535(CHEMBL5194282)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599537(CHEMBL5180580)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599535(CHEMBL5194282)
Affinity DataIC50: 1.45E+3nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50199113(CHEMBL3955013)
Affinity DataIC50: 1.70E+3nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599538(CHEMBL5206234)
Affinity DataIC50: 2.34E+3nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599541(CHEMBL5170088)
Affinity DataIC50: 2.39E+3nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50199113(CHEMBL3955013)
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599534(CHEMBL5169570)
Affinity DataIC50: 3.09E+3nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599544(CHEMBL5179173)
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599539(CHEMBL5169631)
Affinity DataIC50: 5.58E+3nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599540(CHEMBL5203635)
Affinity DataIC50: 5.96E+3nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC pre-incubated for 18 hrs by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599538(CHEMBL5206234)
Affinity DataIC50: 6.51E+3nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599541(CHEMBL5170088)
Affinity DataIC50: 1.00E+4nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599540(CHEMBL5203635)
Affinity DataIC50: 1.00E+4nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599543(CHEMBL5193131)
Affinity DataIC50: 1.00E+4nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599542(CHEMBL5173002)
Affinity DataIC50: 1.00E+4nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599544(CHEMBL5179173)
Affinity DataIC50: 1.00E+4nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599543(CHEMBL5193131)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599533(CHEMBL5204177)
Affinity DataIC50: 4.49E+4nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599542(CHEMBL5173002)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599546(CHEMBL5170796)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed