Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50015879
TargetPoly [ADP-ribose] polymerase 1(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590271(CHEMBL5198711)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP1 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP11(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP11 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP4(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590271(CHEMBL5198711)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590269(CHEMBL5187963)
Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP2 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP4(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590270(CHEMBL5181770)
Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP4(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590274(CHEMBL5200299)
Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP4(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590273(CHEMBL5176271)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590270(CHEMBL5181770)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP2 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590270(CHEMBL5181770)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of N-terminal His-tagged full length human PARP1 expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP4(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590272(CHEMBL5184065)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant human PARP4 brct-catalytic domain (369 to 573 residues) expressed in Escherichia coli BL21 (DE3) prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
Initial Therapeutics

Curated by ChEMBL
LigandPNGBDBM50590275(CHEMBL5173275)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of N-terminal His-tagged human PARP15 catalytic domain expressed in Escherichia coli BL21 (DE3) preincubated with 6-a-NAD+ for 5 to 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed