Compile Data Set for Download or QSAR
Report error Found 97 Enz. Inhib. hit(s) with all data for entry = 50018517
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609061(CHEMBL5269567)
Affinity DataEC50:  0.0900nMAssay Description:Agonist activity at FXR in human HeLa cells by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609062(CHEMBL5271104)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at FXR in human HeLa cells by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetRNA-binding protein FXR2(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609019(CHEMBL5267458)
Affinity DataEC50:  0.350nMAssay Description:Agonist activity at FXR2 in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetRNA-binding protein FXR2(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50185708(CHEMBL3822464)
Affinity DataEC50:  0.75nMAssay Description:Agonist activity at FXR2 in human HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609057(CHEMBL5278385)
Affinity DataEC50: <1nMAssay Description:Agonist activity at human FXR in expressed in CHO cells by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609056(CHEMBL5273044)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at FXR (unknown origin) incubated for 180 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM532159(US11208418, Example 6)
Affinity DataEC50:  2nMAssay Description:Agonist activity at FXR (unknown origin) incubated for 15 mins by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609027(CHEMBL5270341)
Affinity DataEC50:  2nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609067(CHEMBL5280183)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human FXR incubated for 24 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM532112(US11208418, Example 1)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at FXR (unknown origin) incubated for 15 mins by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50241116(CHEMBL4066332)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609024(CHEMBL5289009)
Affinity DataEC50:  5nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM532160(US11208418, Example 7)
Affinity DataEC50:  7.40nMAssay Description:Agonist activity at FXR (unknown origin) incubated for 15 mins by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609043(CHEMBL5290473)
Affinity DataEC50:  7.70nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609054(CHEMBL5275893)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at FXR (unknown origin) incubated for 180 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM532158(US11208418, Example 3)
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at FXR (unknown origin) incubated for 15 mins by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609046(CHEMBL5270235)
Affinity DataEC50:  9nMAssay Description:Agonist activity at human GST-tagged FXR incubated for 1 hrs by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50570171(CHEMBL4870713)
Affinity DataEC50:  9.10nMAssay Description:Agonist activity at FXR in human HeLa cells by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609023(CHEMBL5268548)
Affinity DataEC50:  10nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609030(CHEMBL5281263)
Affinity DataEC50:  10nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50570146(CHEMBL4860451)
Affinity DataEC50:  10nMAssay Description:Agonist activity at FXR in human HeLa cells by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609026(CHEMBL5266939)
Affinity DataEC50:  12nMAssay Description:Agonist activity at FXR in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609026(CHEMBL5266939)
Affinity DataEC50:  12nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609047(CHEMBL5273113 | US12215098, Formula (I))
Affinity DataEC50:  13nMAssay Description:Agonist activity at human GST-tagged FXR incubated for 1 hrs by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50544034(CHEMBL4642141)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human FXR by lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609029(CHEMBL5276532)
Affinity DataEC50:  13nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609068(CHEMBL5288227)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human FXR incubated for 24 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609053(CHEMBL5268480)
Affinity DataEC50:  15nMAssay Description:Agonist activity at FXR (unknown origin) incubated for 180 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609022(CHEMBL5267052)
Affinity DataEC50:  17nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609065(CHEMBL5288616)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human FXR incubated for 24 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609066(CHEMBL5274488)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human FXR incubated for 24 hrs by luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609049(CHEMBL5287502)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human GST-tagged FXR incubated for 1 hrs by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609048(CHEMBL5278159)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human GST-tagged FXR incubated for 1 hrs by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50241116(CHEMBL4066332)
Affinity DataEC50:  20nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609028(CHEMBL5279195)
Affinity DataEC50:  21nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609025(CHEMBL5270645)
Affinity DataEC50:  23nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609060(CHEMBL5290019)
Affinity DataEC50:  26nMAssay Description:Agonist activity at FXR in human HeLa cells by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609055(CHEMBL5266961)
Affinity DataEC50:  27nMAssay Description:Agonist activity at FXR (unknown origin) incubated for 180 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609012(CHEMBL5271527)
Affinity DataEC50: <30nMAssay Description:Agonist activity at human FXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609020(CHEMBL5266567)
Affinity DataEC50: <30nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609013(CHEMBL5279682)
Affinity DataEC50: <30nMAssay Description:Agonist activity at human FXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609014(CHEMBL5272555)
Affinity DataEC50: <30nMAssay Description:Agonist activity at human FXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609015(CHEMBL5283322)
Affinity DataEC50: <30nMAssay Description:Agonist activity at human FXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50544035(CHEMBL4643503)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human FXR by lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609021(CHEMBL5275000)
Affinity DataEC50:  34nMAssay Description:Agonist activity at FXR in HEK293T cells by steady-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609045(CHEMBL5281579)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human GST-tagged FXR incubated for 1 hrs by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609044(CHEMBL5267517)
Affinity DataEC50:  43nMAssay Description:Agonist activity at human GST-tagged FXR incubated for 1 hrs by alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50544032(CHEMBL4643030)
Affinity DataEC50:  44nMAssay Description:Agonist activity at human FXR by lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609036(CHEMBL5267810)
Affinity DataEC50: <50nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
University of Health Sciences and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609037(CHEMBL5266846)
Affinity DataEC50: <50nMAssay Description:Agonist activity at FXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
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