Compile Data Set for Download or QSAR
Report error Found 90 Enz. Inhib. hit(s) with all data for entry = 50014847
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580332(CHEMBL5081575)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580332(CHEMBL5081575)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580346(CHEMBL5074750)
Affinity DataIC50: 0.380nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580343(CHEMBL5086585)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580347(CHEMBL5091091)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580331(CHEMBL5083517)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580333(CHEMBL5081508)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580338(CHEMBL5077855)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580334(CHEMBL5081335)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580339(CHEMBL5084226)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580344(CHEMBL5075134)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580342(CHEMBL5088958)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580340(CHEMBL5078472)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580331(CHEMBL5083517)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580335(CHEMBL5092327)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580342(CHEMBL5088958)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580343(CHEMBL5086585)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580337(CHEMBL5081090)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580345(CHEMBL5081851)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580337(CHEMBL5081090)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580341(CHEMBL5091578)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580339(CHEMBL5084226)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580334(CHEMBL5081335)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580338(CHEMBL5077855)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580340(CHEMBL5078472)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580335(CHEMBL5092327)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580333(CHEMBL5081508)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580347(CHEMBL5091091)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580344(CHEMBL5075134)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580330(CHEMBL5075263)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580346(CHEMBL5074750)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580341(CHEMBL5091578)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580330(CHEMBL5075263)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580346(CHEMBL5074750)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human HGFA serine protease domain using Boc-QLR-AMC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProthrombin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580335(CHEMBL5092327)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant thrombin (unknown origin) using D-Phe-Pip-Arg-pNA as substrate preincubated for 30 mins followed by substrate addition by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580336(CHEMBL5091873)
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580345(CHEMBL5081851)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580335(CHEMBL5092327)
Affinity DataIC50: 118nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected Sf9 insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580336(CHEMBL5091873)
Affinity DataIC50: 136nMAssay Description:Inhibition of recombinant human C-terminal 10-His tagged hepsin (Arg45 to Leu417) expressed in mouse myeloma cells using Boc-QAR-AMC as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580332(CHEMBL5081575)
Affinity DataIC50: 155nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected Sf9 insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580347(CHEMBL5091091)
Affinity DataIC50: 678nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected Sf9 insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580331(CHEMBL5083517)
Affinity DataIC50: 723nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected Sf9 insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580346(CHEMBL5074750)
Affinity DataIC50: 770nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected Sf9 insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetProthrombin(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580344(CHEMBL5075134)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of recombinant thrombin (unknown origin) using D-Phe-Pip-Arg-pNA as substrate preincubated for 30 mins followed by substrate addition by c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580330(CHEMBL5075263)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected Sf9 insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580336(CHEMBL5091873)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected Sf9 insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580343(CHEMBL5086585)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected Sf9 insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580339(CHEMBL5084226)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected Sf9 insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580344(CHEMBL5075134)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected Sf9 insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Washington University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50580334(CHEMBL5081335)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected Sf9 insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
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