Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50014274
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574370(CHEMBL4846168 | US20230271956, Compound 1)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574373(CHEMBL4873965 | US20230271956, Compound 60)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574374(CHEMBL4850648 | US20230271956, Compound 87)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574375(CHEMBL4876400 | US20230271956, Compound 102)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574370(CHEMBL4846168 | US20230271956, Compound 1)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574371(CHEMBL4867121 | US20230271956, Compound 55)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574372(CHEMBL4848186 | US20230271956, Compound 59)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574374(CHEMBL4850648 | US20230271956, Compound 87)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574370(CHEMBL4846168 | US20230271956, Compound 1)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574371(CHEMBL4867121 | US20230271956, Compound 55)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574372(CHEMBL4848186 | US20230271956, Compound 59)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574373(CHEMBL4873965 | US20230271956, Compound 60)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574375(CHEMBL4876400 | US20230271956, Compound 102)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574374(CHEMBL4850648 | US20230271956, Compound 87)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into histones by microbeta scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574371(CHEMBL4867121 | US20230271956, Compound 55)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574372(CHEMBL4848186 | US20230271956, Compound 59)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant ACSS2 incubated for 180 mins by AMP Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574373(CHEMBL4873965 | US20230271956, Compound 60)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAcetyl-coenzyme A synthetase, cytoplasmic(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574375(CHEMBL4876400 | US20230271956, Compound 102)
Affinity DataIC50: 1nMAssay Description:Inhibition of ACSS2 in human HCT-15 cells assessed as inhibition of 14C acetate incorporation into fatty acids by microbeta scintillation counting an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed