Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50014376
TargetCytochrome P450 3A4(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50575375(CHEMBL4875016)
Affinity DataIC50: 190nMAssay Description:Inhibition of human CYP3A4 using testosterone as a substrate by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50575374(CHEMBL4876338)
Affinity DataIC50: 290nMAssay Description:Inhibition of human CYP3A4 using testosterone as a substrate by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50575373(CHEMBL4857273)
Affinity DataIC50: 940nMAssay Description:Inhibition of human CYP3A4 using testosterone as a substrate by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50575375(CHEMBL4875016)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human CYP2C9 using 7-methoxy-4(trifluoromethyl coumarin) as a substrate incubated for 15 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50575374(CHEMBL4876338)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C9 using 7-methoxy-4(trifluoromethyl coumarin) as a substrate incubated for 15 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50575374(CHEMBL4876338)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2D6 using 3-[2-(N,N-diethylamino)ethyl]-7-methoxy-4-methyl coumarin as a substrate incubated for 45 mins by fluorescence based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50575375(CHEMBL4875016)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2D6 using 3-[2-(N,N-diethylamino)ethyl]-7-methoxy-4-methyl coumarin as a substrate incubated for 45 mins by fluorescence based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed