Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50017575
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50602937(CHEMBL5208912)
Affinity DataIC50: 320nMAssay Description:Inhibition of ROCK2 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK-peptide as substrate incubated for 30 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM14027(AT877 | CHEMBL38380 | 5-(1,4-diazepan-1-ylsulfonyl...)
Affinity DataIC50: 370nMAssay Description:Inhibition of ROCK2 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK-peptide as substrate incubated for 30 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50602938(CHEMBL5204978)
Affinity DataIC50: 730nMAssay Description:Inhibition of ROCK2 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK-peptide as substrate incubated for 30 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50602935(CHEMBL5193582)
Affinity DataIC50: 790nMAssay Description:Inhibition of ROCK2 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK-peptide as substrate incubated for 30 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50602942(CHEMBL5194687)
Affinity DataIC50: 900nMAssay Description:Inhibition of ROCK2 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK-peptide as substrate incubated for 30 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50602936(CHEMBL5186668)
Affinity DataIC50: 2.13E+3nMAssay Description:Inhibition of ROCK2 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK-peptide as substrate incubated for 30 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50602939(CHEMBL5203330)
Affinity DataIC50: 2.33E+3nMAssay Description:Inhibition of ROCK2 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK-peptide as substrate incubated for 30 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50602940(CHEMBL5190627)
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of ROCK2 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK-peptide as substrate incubated for 30 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50602941(CHEMBL5183453)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK2 (unknown origin) using KEAKEKRQEQIAKRRRLSSLRASTSKSGGSQK-peptide as substrate incubated for 30 mins in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed