Compile Data Set for Download or QSAR
Report error Found 271 Enz. Inhib. hit(s) with all data for entry = 50016423
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594825(CHEMBL5198856)
Affinity DataEC50:  0.000515nMAssay Description:Agonist activity at MOP (unknown origin) stably expressed in HEK293 cells assessed as forskolin stimulated cAMP accumulation incubated for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594821(CHEMBL5175179)
Affinity DataEC50:  0.00180nMAssay Description:Agonist activity at MOP (unknown origin) stably expressed in HEK293 cells assessed as forskolin stimulated cAMP accumulation incubated for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594822(CHEMBL5182849)
Affinity DataEC50:  0.00201nMAssay Description:Agonist activity at MOP (unknown origin) stably expressed in HEK293 cells assessed as forskolin stimulated cAMP accumulation incubated for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594820(CHEMBL5176887)
Affinity DataEC50:  0.00400nMAssay Description:Agonist activity at MOP (unknown origin) stably expressed in HEK293 cells assessed as forskolin stimulated cAMP accumulation incubated for 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594821(CHEMBL5175179)
Affinity DataKi:  0.0110nMAssay Description:Displacement of [3H]DAMGO from MOP (unknown origin) stably expressed in HEK293 cells by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594822(CHEMBL5182849)
Affinity DataKi:  0.0140nMAssay Description:Displacement of [3H]DAMGO from MOP (unknown origin) stably expressed in HEK293 cells by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50594844(CHEMBL5199190)
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594865(CHEMBL5186887)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at human MOP stably expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594820(CHEMBL5176887)
Affinity DataKi:  0.0320nMAssay Description:Displacement of [3H]DAMGO from MOP (unknown origin) stably expressed in HEK293 cells by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50594842(CHEMBL5199205)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594825(CHEMBL5198856)
Affinity DataKi:  0.0511nMAssay Description:Displacement of [3H]DAMGO from MOP (unknown origin) stably expressed in HEK293 cells by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50491417(22-THIOCYANATOSALVINORIN A)
Affinity DataEC50:  0.0770nMAssay Description:Agonist activity at human KOP stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50594843(CHEMBL5175678)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50594846(CHEMBL5209004)
Affinity DataKi:  0.0900nMAssay Description:Displacement of [3H]DAGO from rat brain MOP incubated for 90 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50010483(CHEMBL2181202)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]DAMGO from calf thalamus membrane MOP by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50016867((S)-6-Amino-2-((S)-2-{(R)-2-[(S)-2-amino-3-(4-hydr...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity to MOP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50143182(CHEMBL3759167)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]DAMGO from Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594830(CHEMBL5186493)
Affinity DataKi:  0.25nMAssay Description:Binding affinity to MOP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50594838(CHEMBL5171420)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594819(CHEMBL5208747)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]DAMGO from MOP (unknown origin) stably expressed in HEK293 cells by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594826(CHEMBL5197271)
Affinity DataEC50:  0.430nMAssay Description:Agonist activity at human MOP expressed in CHO-K1 cell membrane assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50143183(CHEMBL3759179)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]DAMGO from Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594824(CHEMBL5190232)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]DAMGO from MOP (unknown origin) stably expressed in HEK293 cells by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594836(CHEMBL5199625)
Affinity DataKi:  0.470nMAssay Description:Displacement of [3H]DAMGO from MOP in human SH-SY5Y cells incubated fro 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594827(CHEMBL5171745)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]DAMGO from human MOP expressed in CHO-K1 cell membrane incubated for 60 mins by Microscint-counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50594853(CHEMBL1355638)
Affinity DataKi:  0.5nMAssay Description:Displacement of [3H]DAMGO from calf thalamus membrane MOP by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50059841(CHEMBL278789 | (S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-...)
Affinity DataKi:  0.540nMAssay Description:Binding affinity to MOP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50359546(CHEMBL1927270)
Affinity DataIC50: 0.560nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594818(CHEMBL5173837)
Affinity DataKi:  0.580nMAssay Description:Displacement of [3H]DAMGO from MOP (unknown origin) stably expressed in HEK293 cells by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50491417(22-THIOCYANATOSALVINORIN A)
Affinity DataKi:  0.590nMAssay Description:Displacement of [3H]U69593 from human KOP stably expressed in CHO cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594823(CHEMBL5188741)
Affinity DataKi:  0.610nMAssay Description:Displacement of [3H]DAMGO from MOP (unknown origin) stably expressed in HEK293 cells by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594826(CHEMBL5197271)
Affinity DataKi:  0.630nMAssay Description:Displacement of [3H]DAMGO from human MOP expressed in CHO-K1 cell membrane incubated for 60 mins by Microscint-counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50594854(CHEMBL5169797)
Affinity DataKi:  0.670nMAssay Description:Displacement of [3H]DAMGO from mouse brain cerebellum MOP incubated for 2 hrs by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594828(CHEMBL5198915)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]DAMGO from human MOP expressed in CHO-K1 cell membrane incubated for 60 mins by Microscint-counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50139013(CHEMBL333357 | (S)-N-((S)-1-((S)-1-amino-1-oxo-3-p...)
Affinity DataKi:  0.690nMAssay Description:Displacement of [3H]DAMGO from Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50059841(CHEMBL278789 | (S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-...)
Affinity DataIC50: 0.760nMAssay Description:Antagonist activity at mouse brain homogenate MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50594840(CHEMBL5189745)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50268531(c[L-Ala-D-pro-L-Phe-D-trp] | CHEMBL499595)
Affinity DataIC50: 0.810nMAssay Description:Antagonist activity at human KOP stably expressed in CHO cell membrane assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594827(CHEMBL5171745)
Affinity DataEC50:  0.940nMAssay Description:Agonist activity at human MOP expressed in CHO-K1 cell membrane assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594829(CHEMBL5196331)
Affinity DataKi:  0.960nMAssay Description:Displacement of [3H]DAMGO from human MOP expressed in CHO-K1 cell membrane incubated for 60 mins by Microscint-counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594832(CHEMBL5185581)
Affinity DataKi:  0.980nMAssay Description:Binding affinity to MOP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594828(CHEMBL5198915)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human MOP expressed in CHO-K1 cell membrane assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetKappa-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50143183(CHEMBL3759179)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]-norBNI from Wistar rat brain membrane KOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594843(CHEMBL5175678)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human recombinant MOP expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50594839(CHEMBL5171242)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50059841(CHEMBL278789 | (S)-1-[(S)-2-[2-((S)-2-{(R)-2-[(S)-...)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at guinea pig ileum MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594836(CHEMBL5199625)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at MOP in human SH-SY5Y cells assessed as forskolin stimulated cAMP accumulation incubated for 30 mins by Biotrak-EIA kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50594841(CHEMBL5194625)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of Wistar rat brain membrane MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50010483(CHEMBL2181202)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at guinea pig ileum MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50594829(CHEMBL5196331)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at human MOP expressed in CHO-K1 cell membrane assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Displayed 1 to 50 (of 271 total ) | Next | Last >>
Jump to: