Compile Data Set for Download or QSAR
Report error Found 69 Enz. Inhib. hit(s) with all data for entry = 50017601
TargetHistone deacetylase 6(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of HDAC6 (unknown origin) using FAM-RHKK(Ac)-NH2/FAM-RHKK(trifluoroacetyl)-NH2 as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human full-length C-terminal Flag-His6-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorogenic HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 10nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HDAC6 (1 to 1215 residues) expressed in Sf9 insect cells using fluorogenic HDAC substrate 3 mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603261(CHEMBL5204931)
Affinity DataIC50: 15nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 19nMAssay Description:Inhibition of HDAC3 (unknown origin) using FAM-RHKK(Ac)-NH2/FAM-RHKK(trifluoroacetyl)-NH2 as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603233(CHEMBL5196817)
Affinity DataIC50: 28nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603233(CHEMBL5196817)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human full-length C-terminal Flag-His6-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorogenic HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 61nMAssay Description:Inhibition of HDAC1 (unknown origin) using FAM-RHKK(Ac)-NH2/FAM-RHKK(trifluoroacetyl)-NH2 as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603230(CHEMBL5186622)
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant human full-length C-terminal Flag-His6-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorogenic HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603231(CHEMBL5178597)
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant human full-length C-terminal Flag-His6-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorogenic HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 104nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 301nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603232(CHEMBL5179973)
Affinity DataIC50: 309nMAssay Description:Inhibition of recombinant human full-length C-terminal Flag-His6-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorogenic HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 310nMAssay Description:Inhibition of human full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell using fluorogenic HDAC class 2a substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 524nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603232(CHEMBL5179973)
Affinity DataIC50: 574nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM19410(benzamide-type inhibitor, 3 | CHEMBL27759 | pyridi...)
Affinity DataIC50: 686nMAssay Description:Inhibition of recombinant human full-length C-terminal Flag-His6-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluorogenic HDA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 827nMAssay Description:Inhibition of HDAC8 (unknown origin) using FAM-RHKK(Ac)-NH2/FAM-RHKK(trifluoroacetyl)-NH2 as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603233(CHEMBL5196817)
Affinity DataIC50: 948nMAssay Description:Inhibition of human full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell using fluorogenic HDAC class 2a substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603258(CHEMBL5169697)
Affinity DataIC50: 950nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603244(CHEMBL5193978)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603230(CHEMBL5186622)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell using fluorogenic HDAC class 2a substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50603231(CHEMBL5178597)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50603233(CHEMBL5196817)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603257(CHEMBL5205638)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603251(CHEMBL5186352)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50603232(CHEMBL5179973)
Affinity DataIC50: 1.36E+3nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603230(CHEMBL5186622)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603231(CHEMBL5178597)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603248(CHEMBL5180204)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
LigandPNGBDBM50603230(CHEMBL5186622)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of C-terminal His-tagged human HDAC3 (1 to 428 residues)/N-terminal GST tagged human NCOR2 (395 to 489) expressed in baculovirus infected ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603232(CHEMBL5179973)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell using fluorogenic HDAC class 2a substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603241(CHEMBL5201586)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603245(CHEMBL5187598)
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603237(CHEMBL5189969)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603234(CHEMBL5199180)
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603256(CHEMBL5171894)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603231(CHEMBL5178597)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of human full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell using fluorogenic HDAC class 2a substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603254(CHEMBL5194807)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603252(CHEMBL5206235)
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603239(CHEMBL5199216)
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603243(CHEMBL5189050)
Affinity DataIC50: 3.13E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603259(CHEMBL5170894)
Affinity DataIC50: 3.43E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603260(CHEMBL5200344)
Affinity DataIC50: 3.91E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603253(CHEMBL5206588)
Affinity DataIC50: 4.24E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603246(CHEMBL5174412)
Affinity DataIC50: 4.33E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603250(CHEMBL5189915)
Affinity DataIC50: 4.41E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50005711(GNF-Pf-1011 | CHEBI:46024 | TRICHOSTATIN | Trichos...)
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-fused/C-terminal His-tagged HDAC4 (627 to 1084 residues) expressed in baculovirus infected Sf9 insect ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Nanchang University

Curated by ChEMBL
LigandPNGBDBM50603255(CHEMBL5174901)
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts using color de Lys as substrate measured after 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
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