Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50015886
LigandPNGBDBM50398608(MARIZOMIB)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of 20S proteasome (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50590319(CHEMBL5180773)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of influenza A virus Neuraminidase using 2-(4-methylumbelliferyl)-a-D-acetylneuraminic acid as substrate incubated for 30 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
LigandPNGBDBM50590311(Omuralide | OMURALIDE)
Affinity DataIC50: 49nMAssay Description:Inhibition of 20S proteasome (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50590312(CHEMBL5183332)
Affinity DataIC50: 960nMAssay Description:Inhibition of ROCK2 (unknown origin) by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetRho-associated protein kinase 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50590313(CHEMBL5195796)
Affinity DataIC50: 960nMAssay Description:Inhibition of ROCK2 (unknown origin) by HTRF kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50590317(CHEMBL5207978)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of ACE (unknown origin) using hippuryl-histidyl-leucine as substrate pre-incubated with compound for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50590315(CHEMBL5201393)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50590318(CHEMBL5177969)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of ACE (unknown origin) using hippuryl-histidyl-leucine as substrate pre-incubated with compound for 10 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50590320(CHEMBL5198825)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of N-terminal His6-tagged Mycobacterium tuberculosis H37Rv PTPB using 6,8-difluoromethylumbelliferyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetTriple specificity protein phosphatase PtpB(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50590321(CHEMBL5204753)
Affinity DataIC50: 3.01E+4nMAssay Description:Inhibition of N-terminal His6-tagged Mycobacterium tuberculosis H37Rv PTPB using 6,8-difluoromethylumbelliferyl phosphate as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50590314(CHEMBL5180422)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50590316(CHEMBL5172902)
Affinity DataIC50: 1.41E+6nMAssay Description:Inhibition of alpha-Glucosidase (unknown origin) using pNPG as substrate incubated for 20 mins by micro plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed