Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50018536
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Jinany
Curated by ChEMBL
University of Jinany
Curated by ChEMBL
Affinity DataKd: 82nMAssay Description:Binding affinity to PRC2 complex of EZH2-EED-SUZ12 (unknown origin) assessed as dissociation constant by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
Affinity DataKd: 1.5nMAssay Description:Binding affinity to EED (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.320nMAssay Description:Binding affinity to C-terminal histidine tagged EED (unknown origin) expressed in Escherichia coli BL21(DE3) incubated for 15 mins by fluorescence po...More data for this Ligand-Target Pair
Affinity DataKd: 2.82E+3nMAssay Description:Binding affinity to EED (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Displacement of H3K27me3 from EED (unknown origin) by competitive binding assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Jinany
Curated by ChEMBL
University of Jinany
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of PRC2 complex of EZH2-EED-SUZ12 (unknown origin) using human nucleosome as substrate incubated for 70 mins in presence of [3H]SAMMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 890nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.57E+3nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.76E+3nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.16E+4nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
