Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50017147
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600005(CHEMBL5195268)
Affinity DataIC50: 30nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 45nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600003(CHEMBL5201228)
Affinity DataIC50: 55nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50050549(GSK2140944 | Gepotidacin)
Affinity DataIC50: 60nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600006(CHEMBL5172158)
Affinity DataIC50: 90nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600007(CHEMBL5182200)
Affinity DataIC50: 105nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600004(CHEMBL5184104)
Affinity DataIC50: 220nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600009(CHEMBL5177076)
Affinity DataIC50: 340nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600008(CHEMBL5198597)
Affinity DataIC50: 460nMAssay Description:Inhibition of Escherichia coli DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600011(CHEMBL5205047)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600007(CHEMBL5182200)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600010(CHEMBL5184352)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600003(CHEMBL5201228)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600018(CHEMBL5199405)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600013(CHEMBL5194618)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600014(CHEMBL5172094)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600012(CHEMBL5190832)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600017(CHEMBL5195721)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600003(CHEMBL5201228)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of human topoisomerase 2 assessed as reduction in decatenationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600015(CHEMBL5206169)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600004(CHEMBL5184104)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600016(CHEMBL5170129)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50050549(GSK2140944 | Gepotidacin)
Affinity DataIC50: 5.52E+4nMAssay Description:Inhibition of human topoisomerase 2 assessed as reduction in decatenationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600005(CHEMBL5195268)
Affinity DataIC50: 7.28E+4nMAssay Description:Inhibition of human topoisomerase 2 assessed as reduction in decatenationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600006(CHEMBL5172158)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 2 assessed as reduction in decatenationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600007(CHEMBL5182200)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 2 assessed as reduction in decatenationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600004(CHEMBL5184104)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 2 assessed as reduction in decatenationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600008(CHEMBL5198597)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 2 assessed as reduction in decatenationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600009(CHEMBL5177076)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 2 assessed as reduction in decatenationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 2 assessed as reduction in decatenationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600009(CHEMBL5177076)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600008(CHEMBL5198597)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600006(CHEMBL5172158)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50600005(CHEMBL5195268)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM50050549(GSK2140944 | Gepotidacin)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Redx Anti-Infectives

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERG by Ionworks electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed